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Patial(M),Kesari(KK),Kumar(D) Crit Rev Oncol Hematol 2026-08-11

...BRCA1/2 deficiency and loss of PTEN enable immune evasion by triggering anti-tumor response via cGAS/STING pathway and r...

Kowalewski(HS),Wessels(F),Banna(GL),Gandur... Urol Oncol 2026-08-11

...BRCA1/2, as well as selected additional DDR genes. To expand the population that may benefit from PARPi therapy, multipl...

Murachelli(AG),El Oualid(F),Sixma(TK) Nat Commun 2026-08-11

...BRCA1-A complex is a multi-subunit, metallo-deubiquitinating enzyme (metallo-DUB) involved in genome maintenance. BRCA1-...

Foglizzo(M),Datta(A),Degtjarik(O),Perera(H... Nat Commun 2026-08-11

...BRCA1-BARD1 to form the BRCA1-A supercomplex, which recognises K63-linked ubiquitin chains at DNA damage sites. ARISC-RA...

Bouwmeester(AB),Gootzen(TA),Nobbenhuis(M),... Histopathology 2026-08-12

...BRCA1/2 pathogenic variant carriers are at increased risk for high-grade serous carcinoma (HGSC) and are therefore advis...

Lang(Y),Deng(M),Yang(J) Front Pharmacol None

...BRCA1/2 mutations. The addition of apatinib, an anti-angiogenic agent, enhances treatment outcomes. However, the economi...

Shern(TP),Chamberlain(V),Holt(LR),Gadd(MA)... Breast Cancer Res Treat 2026-08-12

...BRCA1/2 mutations (38.9% vs. 7.2%, p < 0.001), bilateral surgery (92.6% vs. 67.7%, p < 0.001), and sentinel lymph node b...

Lynce(F),Ru(M),Luo(L),Miranda(M),Xu(X),Isa... Breast Cancer Res Treat 2026-08-12

...BRCA1/BRCA2 mutation (BRCAm) is not well characterized. This retrospective, observational study explored the real-world ...

Sanguedolce(F),Mazzucchelli(R),Conteduca(V... Diagnostics (Basel) 2026-07-27

BRCA1/2 alterations have emerged as clinically relevant biomarkers in prostate cancer because of their prognostic signif...

Song(H),Jia(Y),Qiu(X),Long(T),Yang(W) Front Pharmacol None

...BRCA1, SERPINA1, and LGALS3. Molecular docking confirmed stable binding of Galanin to the proteins encoded by these gene...