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TP53 BRCA1 CRISPR single-cell cancer

Chen(Jie),Lan(Tian),Zhang(Weimin),Dong(Lij... Arch Biochem Biophys 2015-07-20

...BRCA1, under the control of Src. Furthermore, dasatinib could sensitize ESCC cells to another platin-based agent, carbop...

Papaconstantinou(Ioannis),Mantzos(Dionysio... J BUON 2015-04-30

...BRCA1 and BRCA2 genes. The second most common type of malignancy was colorectal cancer (24%); 5 developed 2 PMNs, wherea...

Scott(Clare L),Swisher(Elizabeth M),Kaufma... J Clin Oncol 2015-06-15

...BRCA1 or BRCA2 seem to be particularly sensitive. However, it is also becoming clear that germline BRCA1/2 mutations are...

Vail(Paris J),Morris(Brian),van Kan(Aric),... J Community Genet 2015-09-14

...BRCA1 and BRCA2 testing. We compared the clinical classifications of these variants among five publicly accessible BRCA1...

Batenburg(Nicole L),Thompson(Elizabeth L),... EMBO J 2015-08-19

...BRCA1, RPA and Rad51 proteins to damaged chromatin but promotes the formation of 53BP1-Rif1 damage foci in S and G2 cell...

Spurdle(Amanda B),Couch(Fergus J),Parsons(... Breast Cancer Res 2015-11-09

...BRCA1/2 (CIMBA) and the Breast Cancer Association Consortium (BCAC) to reassess histopathological predictors of BRCA1 an...

Del Chiaro(Marco),Verbeke(Caroline S),Kart... JAMA Surg 2015-08-31

...BRCA1 mutation (2.5%). In 16 patients (40%), MRI revealed a pancreatic lesion: intraductal papillary mucinous neoplasia ...

Nasedkina(T V),Gromyko(O E),Emel'ianova(M ... Mol Biol (Mosk) 2015-08-04

...BRCA1/2 and CHEK2 mutations were found in 33 (8.0%) BC patients. The most frequent mutation was BRCA1 5382insC, occurred...

Ellison(Gillian),Huang(Shuwen),Carr(Hedley... BMC Clin Pathol 2015-04-10

Germline mutations in BRCA1 or BRCA2 lead to a high lifetime probability of developing ovarian or breast cancer. These g...

Lim(Annette M),Candiloro(Ida Lm),Wong(Nich... Clin Epigenetics 2015-04-10

...BRCA1, ERCC1, and ATM. The most frequently methylated loci were RUNX3 (18/108 methylated) and ABO (22/107 methylated). I...

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