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A porcine model system of BRCA1 driven breast cancer.

Donninger(Howard),Hobbing(Katharine),Schmidt… Front Genet 2015-09-18

BRCA1 is a breast and ovarian tumor suppressor. Hereditary mutations in BRCA1 result in a predisposition to breast cance...

Epidemiological and clinicopathological characteristics of BRCA-positive and BR…

Triantafyllidou(Olga),Vlachos(Ioannis S),Apo… J BUON 2015-11-12

...BRCA1 mutation carriers (BRCA1mut) and non-carriers (non-BRCA1) in a Greek group of BC patients (n=321).,Data were colle...

Genetic determinants of uterine fibroid size in the multiethnic NIEHS uterine f…

Aissani(Brahim),Zhang(Kui),Wiener(Howard) Int J Mol Epidemiol Genet 2015-09-29

...BRCA1, reached promising associations. In the design that included the controls, several genes of potential relevance to...

Characteristics of ovarian tumors of low malignant potential in BRCA mutation c…

Matsuo(Koji),Tierney(Katherine E),Schneider(… Gynecol Oncol Rep 2015-10-01

...BRCA1 mutation, and presence of invasive implants may be characteristics of BRCA carriers with ovarian LMP.

Multigene panel analysis identified germline mutations of DNA repair genes in b…

Hirotsu(Yosuke),Nakagomi(Hiroshi),Sakamoto(I… Mol Genet Genomic Med 2015-10-05

Approximately 5-10% of all breast and/or ovarian cancer cases are considered as inherited. BRCA1 and BRCA2 tumor suppres...

Delineation of gastric cancer subtypes by co-regulated expression of receptor t…

Li(Shu-Chun),Ma(Rong),Wu(Jian-Zhong),Xiao(Xi… Am J Transl Res 2015-09-23

...BRCA1, RRM1, TUBB3, STMN1, TYMS and TOP2A) and five receptor tyrosine kinases (RTKs) (EGFR, ERBB2, PDGFRB, VEGFR1 and VE...

Bilateral salpingo-oophorectomy and adhesiolysis with single port access laparo…

Angioni(S),Pontis(A),Sorrentino(F),Nappi(L) Eur J Gynaecol Oncol 2015-10-05

...BRCA1 mutation. As fimbria could be considered the site of origin for many serous carcinomas in BRCA mutation carriers, ...

BRCA1 Mutation: A Predictive Marker for Radiation Therapy?

Kan(Charlene),Zhang(Junran) Int J Radiat Oncol Biol Phys 2015-12-21

...BRCA1 encoded by the tumor suppressor gene BRCA1 regulates all DSB repair pathways. Given that DSBs represent the most b...

The role of BRCA1 and BRCA2 mutations in prostate, pancreatic and stomach cance…

Cavanagh(Helen),Rogers(Katherine M A) Hered Cancer Clin Pract 2015-08-03

...BRCA1/2 with cancers at other sites within the body. This review examines the association of BRCA1/2 germline gene mutat...

Biomarkers in triple negative breast cancer: A review.

Yadav(Budhi S),Chanana(Priyanka),Jhamb(Swaty) World J Clin Oncol 2015-12-17

...BRCA1 related breast cancers. Management of these tumours is a challenge to the clinician because of its aggressive beha...

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