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González(Eduardo G),Rancati(Alberto O) Gland Surg 2015-12-08

...BRCA1, BRCA2 mutations, and also due to new staging standards and use of nuclear magnetic resonance. This increase in th...

Double Heterozygosity of BRCA2 and STK11 in Familial Breast Cancer Detected by …

Ataei-Kachouei(Mojgan),Nadaf(Javad),Akbari(M… Iran J Public Health 2015-11-20

...BRCA1 and BRCA2 genes are responsible for approximately 25-30% of dominantly inherited familial breast cancers; still a ...

A phase II evaluation of the potent, highly selective PARP inhibitor veliparib …

Coleman(Robert L),Sill(Michael W),Bell-McGui… Gynecol Oncol 2015-09-01

Veliparib is a potent small molecule inhibitor of PARP-1/2, which is cytotoxic in tumor cells with deficiencies in BRCA1...

BRCA genetic screening in Middle Eastern and North African: mutational spectrum…

Laraqui(Abdelilah),Uhrhammer(Nancy),Rhaffoul… Dis Markers 2015-12-08

The contribution of BRCA1 mutations to both hereditary and sporadic breast and ovarian cancer (HBOC) has not yet been th...

Phenotypic analysis of familial breast cancer: comparison of BRCAx tumors with …

Aloraifi(F),Alshehhi(M),McDevitt(T),Cody(N),… Eur J Surg Oncol 2015-06-22

...BRCA1/BRCA2 negative familial breast cancer (BRCAx) to BRCA1-positive, BRCA2-positive and sporadic cases without a famil...

Lipid and Metabolite Deregulation in the Breast Tissue of Women Carrying BRCA1 …

Ramadan(Saadallah),Arm(Jameen),Silcock(Judit… Radiology 2015-08-06

...BRCA1 (n = 9) or BRCA2 (n = 14) gene mutations and were compared with images in healthy control subjects with no family ...

BRCA1 and BRCA2 common mutations in iranian breast cancer patients: a meta anal…

Forat-Yazdi(Mohammad),Neamatzadeh(Hossein),S… Asian Pac J Cancer Prev 2015-12-08

...BRCA1 and BRCA2 associated with breast cancer have been reported in different populations. However, the common BRCA1 and...

Prognostic relevance of acquired uniparental disomy in serous ovarian cancer.

Tuna(Musaffe),Ju(Zhenlin),Smid(Marcel),Amos(… Mol Cancer 2015-09-16

...BRCA1 were associated with recurrence-free survival time. In Cox multivariable proportional hazards analysis, whole-chro...

Two decades beyond BRCA1/2: Homologous recombination, hereditary cancer risk an…

Walsh(Christine S) Gynecol Oncol 2015-08-24

Almost exactly 20 years after their discovery, the BRCA1 and BRCA2 genes have become the target of the first "personaliz...

Splicing analysis of 14 BRCA1 missense variants classifies nine variants as pat…

Ahlborn(Lise B),Dandanell(Mette),Steffensen(… Breast Cancer Res Treat 2015-12-04

...BRCA1 gene predispose carriers to early onset breast and ovarian cancer. Clinical genetic screening of BRCA1 often revea...

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