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TP53 BRCA1 CRISPR single-cell cancer

Nagasawa(Satoi),Sedukhina(Anna S),Nakagawa... PLoS One 2015-12-29

...BRCA1 in triple negative breast cancer. This phenomenon is also observed in in vitro models of basal-like breast cancer,...

Parameswaran(Balaji),Chiang(Huai-Chin),Lu(... Cell Cycle 2015-12-02

...BRCA1 delays end resection and the dispersion of BRCA1 from DSBs but does not affect the assembly of Mre11/Rad50/NBS1 (M...

Hedgepeth(Serena C),Garcia(M Iveth),Wagner... J Biol Chem 2015-05-29

...BRCA1. BRCA1 binding directly sensitizes the IP3R to its ligand, IP3. BRCA1 is recruited to the ER during apoptosis in a...

Björkman(Andrea),Qvist(Per),Du(Likun),Bart... Proc Natl Acad Sci U S A 2015-05-04

Breast cancer type 1 susceptibility protein (BRCA1) has a multitude of functions that contribute to genome integrity and...

Jhuraney(Ankita),Velkova(Aneliya),Johnson(... J Med Genet 2015-12-21

...BRCA1 missense variants. BRCA1 Circos is a web-based visualisation tool based on the freely available Circos software pa...

Laskar(Ruhina S),Talukdar(Fazlur R),Choudh... Tumour Biol 2015-10-23

...BRCA1 and GSTP1). HPV DNA was detected in 34/93 (36.5 %) colorectal tumour tissues, HPV 18 being the predominant high-ri...

Francis(Jeffrey C),Melchor(Lorenzo),Campbe... J Pathol 2015-07-20

...BRCA1/2-deficient cancers was not common in the genome of these mouse tumours. Although a useful model, there are some d...

Lai(Stella),Brookes(Clare),Prosser(Debra O... Sultan Qaboos Univ Med J 2015-02-16

...BRCA1 and BRCA2 (BRCA1/2) genes by Sanger-based sequencing as well as to assess a MPS approach encompassing multiplex po...

Aleskandarany(Mohammed),Caracappa(Daniela)... Breast Cancer Res Treat 2015-11-20

...BRCA1-mutated (n = 48), and BRCA2-mutated (n = 27) BC. The following DNA damage response (DDR) markers are used; BRCA1, ...

Al-Kaabi(M M),Alshareeda(A T),Jerjees(D A)... Br J Cancer 2015-04-30

...BRCA1, KU70/KU80, DNA-PKCα and BARD1) and sumoylation (UBC9 and PIASγ) biomarkers. Subcellular localisation of pCHK1 was...

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