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INPP4B and RAD50 have an interactive effect on survival after breast cancer.

Dai(Xiaofeng),Fagerholm(Rainer),Khan(Sofia... Breast Cancer Res Treat 2015-09-28

...BRCA1, RB1, TP53, PTEN, and INPP4B. In this study, we investigate whether these co-deleted genes have interactive effect...

Impact of chemotherapy on telomere length in sporadic and familial breast can...

Benitez-Buelga(C),Sanchez-Barroso(L),Galla... Breast Cancer Res Treat 2015-09-28

Recently, we observed that telomeres of BRCA1/2 mutation carriers were shorter than those of controls or sporadic breast...

Identification of six new susceptibility loci for invasive epithelial ovarian...

Kuchenbaecker(Karoline B),Ramus(Susan J),T... Nat Genet 2015-04-14

...BRCA1 and BRCA2 mutation carriers who are at high risk of EOC. After imputation to 1000 Genomes Project data, we assesse...

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped tel...

Badie(Sophie),Carlos(Ana Rita),Folio(Cecil... EMBO J 2015-03-24

...BRCA1, together with its interacting partner CtIP, both acting in end resection, also promotes end-joining of uncapped t...

Olaparib effective in four advanced cancers.

Cancer Discov 2015-09-10

...BRCA1 or BRCA2.

DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity.

Stoepker(Chantal),Faramarz(Atiq),Rooimans(... DNA Repair (Amst) 2015-07-17

The encouraging response rates of BRCA1- and BRCA2-mutated cancers toward PARP inhibitors make it worthwhile to identify...

BRCA1 promoter hypermethylation signature for early detection of breast cance...

Truong(Phuong Kim),Lao(Thuan Duc),Doan(Tha... Asian Pac J Cancer Prev 2015-08-24

...BRCA1 gene, belonged to the tumor suppressor gene family, as the biomarker for breast cancer in Vietnamese population, s...

Cullin 4A and 4B ubiquitin ligases interact with γ-tubulin and induce its pol...

Thirunavukarasou(Anand),Govindarajalu(Goku... Mol Cell Biochem 2015-09-29

...BRCA1 ubiquitin ligases localize on centrosome region and regulate the centrosome duplication cycle for genomic stabilit...

BAP1 and BRAFV600E expression in benign and malignant melanocytic proliferati...

Piris(Adriano),Mihm(Martin C),Hoang(Mai P) Hum Pathol 2015-03-20

...BRCA1-associated protein 1) is a tumor suppressor gene whose mutations have recently been reported to increase susceptib...

Association of BRCA1/2 defects with genomic scores predictive of DNA damage r...

Timms(Kirsten M),Abkevich(Victor),Hughes(E... Breast Cancer Res 2015-11-09

...BRCA1/2 mutation screening, and BRCA1 promoter methylation data.,BRCA1/2 deleterious mutations were observed in all brea...

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