...BRCA1 or BRCA2 mutations in individual patients, loss of BRCA1 promoter methylation, an alteration in molecular subtype,...
...BRCA1 proteins, suggesting that BAP1 may promote DNA repair partly through stabilizing BRCA1. Furthermore, using the MM ...
...BRCA1 and the positive expression of TopBP1 was observed (P < 0.001, r = 0.326). No significant correlation between BRCA...
...BRCA1, and ATM were observed at substantially higher frequencies (19.3% overall) compared to those in primary prostate c...
...BRCA1 and BRCA2 screening of all women regardless of risk status. Both proposed genetic screening tests raise complicate...
...BRCA1 (46%). HER2 gain, detected by MLPA in 38% of the cases, was in excellent concordance with HER2 results obtained by...
...BRCA1/BRCA2 negative from the United Kingdom Familial Ovarian Cancer Screening Study (UK_FOCSS) after quality-control an...
...BRCA1 mRNA levels. Additionally, by cloning a putative target site from BRCA1's amino acid CDS into a luciferase reporte...
...BRCA1 or BRCA2 mutations have been shown to respond to PARP inhibitors. These responses are partial and transient. In th...
...BRCA1/2 families, we studied the impact of this FANCE splice isoform (FANCEΔ4) on DNA repair processes. We have demonstr...
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