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The importance of analysis of long-range rearrangement of BRCA1 and BRCA2 in ...

Kwong(Ava),Chen(Jiawei),Shin(Vivian Y),Ho(... Cancer Genet 2015-11-17

...BRCA1 and 63 (5.10%) were in BRCA2. LGRs accounted for 6.67% (8 of 120) of all BRCA mutations, whereas 8.77 % (5 of 57) ...

Reversing drug resistance of cisplatin by hsp90 inhibitors in human ovarian c...

Zhang(Zhengmao),Xie(Zhen),Sun(Guangyu),Yan... Int J Clin Exp Med 2015-07-29

...BRCA1 and BRCA2 were more dramatically altered by Hsp90 inhibitors and DDP in combination compared to Hsp90 inhibitors o...

SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection duri...

Alagoz(Meryem),Katsuki(Yoko),Ogiwara(Hidea... Nucleic Acids Res 2015-12-22

...BRCA1 recruitment but at 8 h post IR, BRCA1 foci are smaller and aberrantly positioned compared to control cells. BRCA1 ...

PanGen-Fam: Spanish registry of hereditary pancreatic cancer.

Mocci(E),Guillen-Ponce(C),Earl(J),Marquez(... Eur J Cancer 2015-11-09

...BRCA1 germline mutations. In the second year of prospective PDAC screening, one neuroendocrine tumour and a high-grade d...

Association of family risk and lifestyle/comorbidities in ovarian cancer pati...

Teixeira(Natália),Folgueira(Maria Aparecid... Rev Assoc Med Bras (1992) 2015-12-17

...BRCA1/2 mutation according to the Manchester scoring system, a validated method to assess the likelihood of mutation det...

Overexpression of Raf-1 in basal-like carcinoma of the breast: correlation wi...

Wu(Ping),Li(Xizhou),Wu(Yangmei),Hu(Wei),Wa... Contemp Oncol (Pozn) 2015-03-18

...BRCA1, and p53 protein expression was not significantly different between the Raf-1-positive and Raf-1-negative expressi...

Predictive models for customizing chemotherapy in advanced non-small cell lun...

Bonanno(Laura) Transl Lung Cancer Res 2015-03-25

...BRCA1 in homologous recombination (HR), have demonstrated to further sub-classify low BRCA1 NSCLC tumors, improving the ...

Customized chemotherapy in metastatic non-small cell lung cancer (NSCLC).

Wei(Jia),Moran(Teresa),Zou(Zhengyun),Qian(... Transl Lung Cancer Res 2015-03-25

...BRCA1-A complex, influenced outcome in patients with low BRCA1 expression treated with cisplatin/gemcitabine, and in pat...

Are we ready to use biomarkers for staging, prognosis and treatment selection...

Massuti(Bartomeu),Sanchez(Jose Miguel),Her... Transl Lung Cancer Res 2015-03-25

...BRCA1) are among the most promising potential biomarkers for early disease and their clinical utility is currently being...

Detection of BRCA1 and BRCA2 germline mutations in Japanese population using ...

Hirotsu(Yosuke),Nakagomi(Hiroshi),Sakamoto... Mol Genet Genomic Med 2015-03-24

...BRCA1 and BRCA2 in 135 breast and/or ovarian cancer patients. Deleterious BRCA1 and BRCA2 mutations were detected in 10 ...

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