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Clinical Characteristics of Uveal Melanoma in Patients With Germline BAP1 Mut...

Gupta(Mrinali P),Lane(Anne Marie),DeAngeli... JAMA Ophthalmol 2015-11-10

...BRCA1-associated protein 1 gene) are frequently identified in uveal melanoma. To date, the role of germline BAP1 mutatio...

[Clinicopathologic features observation of ovarian transitional cell tumors].

Wang(Linlin),Dong(Yanguang),Li(Qing),Li(Ho... Zhonghua Bing Li Xue Za Zhi 2015-07-09

...BRCA1. All SCs admixed with TCC and pure HG-SCs were diffusely or heterogeneously positive for WT-1, with a sharp contra...

Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiologi...

Zong(Dali),Callén(Elsa),Pegoraro(Gianluca)... Nucleic Acids Res 2015-08-17

...BRCA1 regulate the balance between NHEJ and HR. 53BP1 promotes CSR in part by mediating synapsis of distal DNA ends, and...

TP53 mutations, tetraploidy and homologous recombination repair defects in ea...

Chien(Jeremy),Sicotte(Hugues),Fan(Jian-Bin... Nucleic Acids Res 2015-11-24

...BRCA1 and BRCA2 mutations were observed in two tumors, with nine showing evidence of a homologous recombination (HR) def...

[Case of encapsulated solid papillary carcinoma with triple-negative and basa...

Popovska(S),Damianova(P),Tomov(S),Dineva(T... Akush Ginekol (Sofiia) 2015-06-04

...BRCA1 in combination with a positive p53 IHC makes this case suitable for genetic testing of BRCA1/BRCA2 susceptibility ...

Impaired adipose tissue expandability and lipogenic capacities as ones of the...

Moreno-Indias(Isabel),Tinahones(Francisco ... J Diabetes Res 2015-12-17

...BrCa1, ZAG, and FABP4). On the other hand, mechanisms involved in adipose tissue expandability are also impaired, predom...

Loss of BAP1 Expression in Basal Cell Carcinomas in Patients With Germline BA...

Mochel(Mark C),Piris(Adriano),Nose(Vania),... Am J Clin Pathol 2015-07-28

...BRCA1-associated protein 1 (BAP1), a tumor suppressor gene, develop a tumor predisposition syndrome (OMIM 614327) with i...

A Comparative Analysis of Breast and Ovarian Cancer-related Gene Mutations in...

Amemiya(Yutaka),Bacopulos(Stephanie),Al-Sh... Anticancer Res 2015-08-06

...BRCA1 and BRCA2 as well as 21 additional genes, including, ATM, BARD1, CDH1, P53, EPCAM, MSH6, and RAD50, which have bee...

Demethoxycurcumin-induced DNA Damage Decreases DNA Repair-associated Protein ...

Ko(Yang-Ching),Lien(Jin-Cherng),Liu(Hsin-C... Anticancer Res 2015-08-06

...BRCA1), O6-methylguanine-DNA methyltransferase (MGMT), mediator of DNA damage checkpoint 1 (MDC1), and p53 (tumor suppre...

[Ethnic aspects of hereditary breast cancer in the region of Siberia].

Cherdyntseva(N V),Pisareva(L F),Ivanova(A ... Vestn Ross Akad Med Nauk 2015-06-12

...BRCA1/2 (BRCA1 5382insC, BRCA1 185delAG, BRCA1 4153delAG, BRCAI T300G, BRCA2 6174delT) in women diagnosed with breast ca...

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