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Withaferin a induces proteasome-dependent degradation of breast cancer suscep...

Zhang(Xuan),Timmermann(Barbara),Samadi(Abb... ISRN Biochem 2015-05-13

...BRCA1 regulation by WA. It was found that WA induced a dose-dependent decrease in HSF1 and BRCA1 protein levels. Further...

KPNA2 is a nuclear export protein that contributes to aberrant localisation o...

Alshareeda(A T),Negm(O H),Green(A R),Nolan... Br J Cancer 2015-09-09

...BRCA1, RAD51, SMC6L1, γH2AX, BARD1, UBC9, PIAS1 and CHK1. High level of KPNA2 was associated not only with cytoplasmic l...

Identification of a Variety of Mutations in Cancer Predisposition Genes in Pa...

Yurgelun(Matthew B),Allen(Brian),Kaldate(R... Gastroenterology 2015-11-09

...BRCA1 or BRCA2; 93% of these met the NCCN criteria for Lynch syndrome testing and 33% met NCCN criteria for BRCA1 and BR...

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation ca...

Heemskerk-Gerritsen(B A M),Seynaeve(C),van... J Natl Cancer Inst 2015-04-27

...BRCA1/2 mutation carriers, but may have been subject to several types of bias. The purpose of this nationwide cohort stu...

Psychosocial Impact of Lynch Syndrome on Affected Individuals and Families.

Galiatsatos(Polymnia),Rothenmund(Heidi),Au... Dig Dis Sci 2015-09-30

...BRCA1 or BRCA2 mutations, but there is a paucity of literature looking at psychosocial impact of LS testing for probands...

FOXK2 transcription factor suppresses ERα-positive breast cancer cell growth ...

Liu(Ying),Ao(Xiang),Jia(Zhaojun),Bai(Xiao-... Sci Rep 2015-11-25

...BRCA1/BARD1, the E3 ubiquitin ligase of ERα. FOXK2 interacted with BARD1 and acted as a scaffold protein for BRCA1/BARD1...

Immunohistochemical analysis in ethinylestradiol-treated breast cancers after...

Omoto(Yoko),Takeshita(Takashi),Yamamoto(Yu... Springerplus 2015-03-16

...BRCA1 was significantly up-regulated by EE2 whereas nuclear staining tended to decrease. Individual comparisons suggeste...

Fertility treatments and invasive epithelial ovarian cancer risk in Jewish Is...

Perri(Tamar),Lifshitz(Dror),Sadetzki(Siega... Fertil Steril 2015-07-16

...BRCA1, 33 carried BRCA2, and 3 had unknown mutations. Fertility treatments were not associated with IEOC risk (age-adjus...

BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma pa...

Laroche-Clary(A),Chaire(V),Le Morvan(V),Ne... Br J Cancer 2015-05-01

...BRCA1 haplotype was associated with trabectedin efficacy in soft-tissue sarcoma (STS) patients.,We analysed BRCA1 single...

Clinicopathological significance of BRCA1 promoter hypermethylation in Thai b...

Saelee(Pensri),Chaiwerawattana(Arkom),Ogaw... Asian Pac J Cancer Prev 2015-10-01

...BRCA1 promoter hypermethylation and expression in breast cancer cases. Sixty-one breast cancers were examined for BRCA1 ...

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