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Polo-like kinase 1 inhibits DNA damage response during mitosis.

Benada(Jan),Burdová(Kamila),Lidak(Tomáš),v... Cell Cycle 2015-09-18

...BRCA1 and 53BP1 are required for homologous recombination and non-homologous end joining, respectively. Whereas mechanis...

[Update on genetic predisposition to prostate cancer].

Cussenot(Olivier),Cancel-Tassin(Géraldine) Bull Cancer 2015-03-31

...BRCA1 gene, must be researched. In contrast, the genetic component of the majority of prostate cancer is polygenic, invo...

Identification by array comparative genomic hybridization of a new amplicon o...

Toffoli(Sébastien),Bar(Isabelle),Abdel-Sat... Breast Cancer Res 2015-11-09

...BRCA1 promoter methylation. Interestingly, BRCA1 promoter methylation was never detected in BRCA1 mutated BC. Gene expre...

Mechanisms of resistance to cabazitaxel.

Duran(George E),Wang(Yan C),Francisco(E Br... Mol Cancer Ther 2015-09-28

...BRCA1 and altered epithelial-mesenchymal transition (EMT) markers are also associated with cabazitaxel resistance in the...

Clinical application of micronucleus test: a case-control study on the predic...

Bolognesi(Claudia),Bruzzi(Paolo),Gismondi(... PLoS One 2015-07-13

...BRCA1/2 genes were associated with an increased micronuclei frequency. Our results do not support a significant role of ...

BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in hum...

Kumaraswamy(E),Wendt(K L),Augustine(L A),S... Oncogene 2015-10-29

...BRCA1, whereas miR-146a levels increase with BRCA1. We show that BRCA1 binds to MIR146A promoter and activates transcrip...

Effect of adriamycin on BRCA1 and PARP-1 expression in MCF-7 breast cancer ce...

Wang(Hui),Lu(Changqing),Tan(Yan),Xie(Jun),... Int J Clin Exp Pathol 2015-07-02

...BRCA1 and PARP-1 in BRCA1 wild-type MCF-7 cells. We used Western blotting to detect BRCA1 and PARP-1 levels in MCF-7 cel...

Prevalence of BRCA1 gene mutation in breast cancer patients in Guangxi, China...

Sun(Liping),Liu(Junjie),Wang(Sida),Chen(Yu... Int J Clin Exp Pathol 2015-07-02

...BRCA1 genes were detected by PCR-DNA sequencing.,About 8.9% (41/463) patients were with 22 BRCA1 mutations (all in exon ...

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma ...

Chai(Kit Man),Wang(Chih-Yen),Liaw(Hung-Jiu... Oncotarget 2015-08-31

We previously found that BRCA1-BRCA2-containing complex subunit 3 (BRCC3) was highly expressed in tumorigenic rat glioma...

Gene expression analysis approach to establish possible links between Parkins...

Karim(Sajjad),Mirza(Zeenat),Kamal(Mohammad... CNS Neurol Disord Drug Targets 2015-07-02

...BRCA1 in DNA damage response, sphingomyelin metabolism, 3- phosphoinositide biosynthesis, acute myeloid leukemia signali...

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