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RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

Sobhian(Bijan),Shao(Genze),Lilli(Dana R),C... Science 2007-06-18

...BARD1 (BRCA1-associated ring domain protein 1) E3 ligase and the deubiquitinating enzyme (DUB) BRCC36 to MDC1-gammaH2AX-...

Crystal structure of the BARD1 BRCT domains.

Birrane(Gabriel),Varma(Ashok K),Soni(Aditi... Biochemistry 2007-08-23

...BARD1 BRCT repeats (residues 568-777) at 1.9 A resolution. The composition and structure of the BARD1 phosphoserine-bind...

Identification of BARD1 splice-isoforms involved in human trophoblast invasio...

Li(Lin),Cohen(Marie),Wu(Jianyu),Sow(Mamado... Int J Biochem Cell Biol 2007-09-27

...BARD1, originally discovered as BRCA1-binding protein, acts in conjunction with BRCA1 as ubiquitin ligase. BARD1 and BRC...

BRCA1 control of steroid receptor ubiquitination.

Heine(George F),Parvin(Jeffrey D) Sci STKE 2007-09-24

...BARD1 (BRCA1-associated RING domain 1), is critical for its role as a tumor suppressor, but its targets, and the consequ...

Transcription-induced CAG repeat contraction in human cells is mediated in pa...

Lin(Yunfu),Wilson(John H) Mol Cell Biol 2007-12-12

...BARD1, which together function as an E3 ligase that can ubiquitinate arrested RNAPII. Treatment with the proteasome inhi...

Identification of sequences that target BRCA1 to nuclear foci following alkyl...

Au(Wendy W Y),Henderson(Beric R) Cell Signal 2007-10-04

...BARD1-binding domain (aa1-304) and the C-terminal sequence aa1078-1312. These sequences individually are ineffective, bu...

Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD...

Huo(Xiang),Hu(Zhibin),Zhai(Xiangjun),Wang(... Breast Cancer Res Treat 2007-06-21

...BARD1. We found that the BARD1 Pro24Ser variant genotypes (24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378...

The BARD1 Cys557Ser variant and breast cancer risk in Iceland.

Stacey(Simon N),Sulem(Patrick),Johannsson(... PLoS Med 2007-02-12

...BARD1. Some breast-cancer-associated BRCA1 missense mutations disrupt the function of the BRCA1/BARD1 complex. It is the...

Fine deletion mapping of chromosome 2q21-37 shows three preferentially delete...

Cengiz(Beyhan),Gunduz(Mehmet),Nagatsuka(Hi... Oral Oncol 2007-11-13

...BARD1, ILKAP, PPP1R7, and ING5, are located. Further molecular analysis of each gene should be performed to clarify thei...

Transcriptosome and serum cytokine profiling of an atypical case of myelodysp...

Mahadevan(Daruka),DiMento(Johanna),Croce(K... Am J Hematol 2007-10-11

...BARD1) and anti-apoptotic genes (PGLYRP, SERPINB2, MPO). Hence, a biomics approach has provided insight into elucidating...

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