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Prevalence of the BLM nonsense mutation, p.Q548X, in ovarian cancer patients ...

Bogdanova(Natalia),Togo(Alexandr V),Ratajs... Fam Cancer 2015-12-30

...BRCA1 mutation). The mutation was not significantly more frequent in cases than in controls (Mantel-Haenszel OR 1.14, 95...

Systems consequences of amplicon formation in human breast cancer.

Inaki(Koichiro),Menghi(Francesca),Woo(Xing... Genome Res 2015-06-15

...BRCA1 tumor suppressor locus. This series of events appeared to be unusually common when examined in larger genomic data...

High risk of in-breast tumor recurrence after BRCA1/2-associated breast cance...

Nilsson(Martin P),Hartman(Linda),Kristoffe... Breast Cancer Res Treat 2015-07-24

...BRCA1/2 mutation carriers. Women with invasive breast cancer and a pathogenic mutation in BRCA1 or BRCA2 were included i...

Evidence for clinical efficacy of mitomycin C in heavily pretreated ovarian c...

Moiseyenko(Vladimir M),Chubenko(Vyacheslav... Med Oncol 2015-11-17

Ovarian carcinomas (OC) arising in BRCA1 and BRCA2 mutation carriers demonstrate pronounced sensitivity to platinum-base...

Frequency of mutations in individuals with breast cancer referred for BRCA1 a...

Tung(Nadine),Battelli(Chiara),Allen(Brian)... Cancer 2015-02-25

...BRCA1 and BRCA2 (BRCA1/2) gene testing using a panel of 25 genes associated with inherited cancer predisposition.,This w...

Two biomarker-directed randomized trials in European and Chinese patients wit...

Moran(T),Wei(J),Cobo(M),Qian(X),Domine(M),... Ann Oncol 2015-07-03

...BRCA1 expression received docetaxel/cisplatin, and those with intermediate/high RAP80 expression and high BRCA1 expressi...

A multi-institutional study of the prevalence of BRCA1 and BRCA2 large genomi...

Seong(Moon-Woo),Cho(Sung Im),Kim(Kyu Hyung... BMC Cancer 2015-06-01

...BRCA1/2 small mutations in 78 (35.3%) out of 221 familial breast cancer patients and BRCA1 LGRs in 3 (2.1%) out of 143 B...

MRI screening of women with hereditary predisposition to breast cancer: diagn...

Santoro(Filippo),Podo(Franca),Sardanelli(F... Breast Cancer Res Treat 2015-05-19

...BRCA1/BRCA2 mutation carriers in the years following diagnosis (74 %). It appears however worth noting that the evolutio...

Association between BRCA1 rs799917 polymorphism and breast cancer risk: A met...

Qin(Ting-ting),Chen(Tao),Zhang(Qian),Du(Ha... Biomed Pharmacother 2015-07-27

Studies investigating the association between the BRCA1 rs799917 polymorphism and breast cancer risk have reported contr...

Population-based screening for breast and ovarian cancer risk due to BRCA1 an...

Gabai-Kapara(Efrat),Lahad(Amnon),Kaufman(B... Proc Natl Acad Sci U S A 2015-04-30

...BRCA1 and BRCA2. For carriers of these mutations, risk-reducing salpingo-oophorectomy significantly reduces morbidity an...

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