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TP53 BRCA1 CRISPR single-cell cancer

Sadr-Nabavi(Ariane),Dastpak(Mahtab),Homaei... Hereditas 2015-04-06

...BRCA1 and BRCA2 genes. Some recent studies demonstrated that BRCA1 mutations are seen in high-risk women with family his...

Blanco(Ana),Gutiérrez-Enríquez(Sara),Santa... Breast Cancer Res Treat 2015-09-21

BRCA1 and BRCA2 are the most well-known breast and ovarian cancer susceptibility genes. Additional genes involved in DNA...

O'Neill(Suzanne C),Mays(Darren),Patenaude(... J Community Genet 2015-01-08

Women tested for mutations in BRCA1/2 genes who have minor-aged children confront difficult decisions about if, when, an...

Liu(Liang),Zhou(Weiying),Cheng(Chun-Ting),... Mol Cancer Res 2015-07-22

...BRCA1 axis were observed in primary breast tumor specimens. By downregulating BRCA1, ATM, and MSH2, TGFβ orchestrates DN...

Vos(Janet R),Teixeira(Natalia),van der Kol... Cancer Epidemiol Biomarkers... 2015-07-08

...BRCA1/2 carriers in the Northern Netherlands (N = 1,050). Carrier and general reference populations were: BRCA1/2 carrie...

Feng(Felix Y),Speers(Corey),Liu(Meilan),Ja... Breast Cancer Res Treat 2015-09-21

...BRCA1 mutational status and that PARP1 activity may serve as a clinically relevant biomarker of response. These studies ...

Rubin(Lisa R),Werner-Lin(Allison),Sagi(Mic... Hum Fertil (Camb) 2015-04-17

Despite research on BRCA1/2 mutation carriers attitudes towards preimplantation genetic diagnosis (PGD), considerably le...

Castillo(Andy),Paul(Atanu),Sun(Baohua),Hua... Cell Rep 2015-08-24

...BRCA1 confer hereditary susceptibility to breast and ovarian cancer. However, somatic mutation of BRCA1 is infrequent in...

Song(Tingjie),Xiao(Shiyan),Yao(Dongbao),Hu... Adv Mater 2015-06-08

...BRCA1 in homogeneous solution at room temperature.

Hiatt(Robert A),Porco(Travis C),Liu(Fengch... Cancer Epidemiol Biomarkers... 2015-07-31

...BRCA1/2 genotype.,In simulating incidence for California in 2000, the separate impact of individual variables was modest...

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