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Analysis of novel mutations in BRCA1 in Iranian families with breast cancer.

Sadr-Nabavi(Ariane),Dastpak(Mahtab),Homaei... Hereditas 2015-04-06

...BRCA1 and BRCA2 genes. Some recent studies demonstrated that BRCA1 mutations are seen in high-risk women with family his...

Hormonal and surgical treatment in trans-women with BRCA1 mutations: a contro...

Colebunders(Britt),T'Sjoen(Guy),Weyers(Ste... J Sex Med 2015-05-13

...BRCA1 mutations have been shown to account for a large proportion of inherited predispositions to breast cancer.,The aim...

A multilevel model of postmenopausal breast cancer incidence.

Hiatt(Robert A),Porco(Travis C),Liu(Fengch... Cancer Epidemiol Biomarkers... 2015-07-31

...BRCA1/2 genotype.,In simulating incidence for California in 2000, the separate impact of individual variables was modest...

Genetic variants in BRIP1 (BACH1) contribute to risk of nonsyndromic cleft li...

Mostowska(Adrianna),Hozyasz(Kamil K),Wójci... Birth Defects Res A Clin Mo... 2015-05-21

...BRCA1, BRIP1, E2F1, MLH1, MRE11A, MSH2, MSH6, NBN, RAD50, and RAD51) was conducted using TaqMan assays in a group of 263...

Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.

Simhadri(Srilatha),Peterson(Shaun),Patel(D... J Biol Chem 2015-01-22

PALB2 links BRCA1 and BRCA2 in homologous recombinational repair of DNA double strand breaks (DSBs). Mono-allelic mutati...

Distinct claudin expression characterizes BRCA1-related breast cancer.

Heerma van Voss(Marise R),van Diest(Paul J... Histopathology 2015-07-29

...BRCA1-related breast cancers in comparison with sporadic controls.,Forty breast cancers in BRCA1 mutation carriers and 4...

RAD51C germline mutations found in Spanish site-specific breast cancer and br...

Blanco(Ana),Gutiérrez-Enríquez(Sara),Santa... Breast Cancer Res Treat 2015-09-21

BRCA1 and BRCA2 are the most well-known breast and ovarian cancer susceptibility genes. Additional genes involved in DNA...

Mammography screening and the risk of breast cancer in BRCA1 and BRCA2 mutati...

Giannakeas(Vasily),Lubinski(Jan),Gronwald(... Breast Cancer Res Treat 2015-09-21

...BRCA1 and BRCA2 carriers. We identified 2,346 women with a BRCA1 (n = 1844) or BRCA2 (n = 502) mutation and no breast ca...

Characterization of dual PTEN and p53-targeting microRNAs identifies microRNA...

Tay(Yvonne),Tan(Shen Mynn),Karreth(Florian... Cell Rep 2015-08-24

...BRCA1, a known miR-638 target. We find that miR-638 overexpression promotes tumorigenesis and demonstrate cooperativity ...

Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells.

Acharya(Samir),Kaul(Zeenia),Gocha(April Sa... PLoS One 2015-04-23

...BRCA1 tumor suppressor. Cells deficient in either BLM or BRCA1 have phenotypes consistent with telomere dysfunction. Alt...

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