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Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict b...

Vollebergh(Marieke A),Lips(Esther H),Neder... Breast Cancer Res 2015-04-16

...BRCA1-mutated breast cancer closely and might also share this hypersensitivity. However, ways to identify HRD in non-BRC...

Applications for breast magnetic resonance imaging.

Pilewskie(Melissa),Morrow(Monica) Surg Oncol Clin N Am 2015-02-12

...BRCA1 or BRCA2 mutations, a family history suggesting a hereditary breast cancer syndrome, or a history of chest wall ra...

Probing structure-function relationships in missense variants in the carboxy-...

Carvalho(Renato S),Abreu(Renata B V),Velko... PLoS One 2015-01-15

Germline inactivating variants in BRCA1 lead to a significantly increased risk of breast and ovarian cancers in carriers...

VEGFR3 inhibition chemosensitizes ovarian cancer stemlike cells through down-...

Lim(Jaeyoung J),Yang(Kun),Taylor-Harding(B... Neoplasia 2015-01-23

...BRCA1 and BRCA2. Inhibition of VEGFR3 in ovarian tumor cells was associated with growth arrest. CD133(+) ovarian cancer ...

Breast cancer: major risk factors and recent developments in treatment.

Majeed(Wafa),Aslam(Bilal),Javed(Ijaz),Khal... Asian Pac J Cancer Prev 2015-01-06

...BRCA1 and BRCA2 genes. Obesity, hormone therapy and use of alcohol are possible causes and over-expression of leptin in ...

Surface plasmon resonance biosensor for label-free and highly sensitive detec...

Li(Yahui),Yan(Yurong),Lei(Yaning),Zhao(Dan... Colloids Surf B Biointerfac... 2015-02-12

...BRCA1 gene related to inherited breast cancer, and the wild-type and mutant-type sequences were successfully discriminat...

Analyzing cell cycle checkpoints in response to ionizing radiation in mammali...

Wang(Bin) Methods Mol Biol 2015-01-22

...BRCA1, Chk2, and p53. Here we describe a series of assays that are often used to analyze cell cycle checkpoints after IR...

Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familia...

De Silva(Sumadee),Tennekoon(Kamani Hemamal... BMC Res Notes 2015-01-20

Majority of mutations found to date in the BRCA1/BRCA2 genes in breast and/or ovarian cancer families are point mutation...

Genetic testing and familial implications in breast-ovarian cancer families.

Oosterwijk(Jan C),de Vries(Jakob),Mourits(... Maturitas 2015-03-30

...BRCA1 and BRCA2 has become incorporated in the diagnostic procedure of patients with breast and/or ovarian cancer. Since...

A multi-institutional study on the association between BRCA1/BRCA2 mutational...

Seong(Moon-Woo),Kim(Kyu Hyung),Chung(Il Yo... Breast Cancer Res Treat 2015-08-18

...BRCA1/2 mutation carriers and 57.1 % of BRCA1 mutation carriers. Conversely, two-thirds of TNBC patients carried BRCA1/2...

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