文献库搜索 | GeneLibs

Kay(J),Harris(MA),Lara Gonzalez(LE),van Ge... Immunooncol Technol 2026-09-00

...BRCA1 (gBRCA1) pathogenic variants (PVs) are the most common cause of inherited breast cancer. Preclinical studies have ...

Kabeer(F),Cochrane(D),Grisdale(C),Lynch(BJ... Gynecol Oncol Rep 2026-08-00

...BRCA1 mutation with somatic loss of heterozygosity (LOH), resulting in biallelic BRCA1 loss. A high HRDetect score (0.96...

Yoshioka(KI),Matsuno(Y),Kusumoto-Matsuo(R) Cancer Sci 2026-08-14

...BRCA1/2 mutations. However, many cancers exhibiting genomic instability occur without detectable defects in canonical re...

Ashour(AM),Alhayyan(A),Alhayyan(R) Medicine (Baltimore) 2026-08-14

...BRCA1/2, and Epidermal Growth Factor Receptor. Breast cancer, colorectal cancer, and non-small cell lung cancer were amo...

Cao(Y),Lewis(Y),Tu(L),Alesi(LR),Stringer(J... Reprod Biomed Online 2026-07-24

...Brca1 deletion [conditional knockout (cKO): Brca1fl/flGdf9cre/+] and wild-type controls (Brca1fl/flGdf9+/+). Young (40-8...

Durán-Toribio(AK),Jiménez-Díaz(IF),Caballé... Crit Rev Oncol Hematol 2026-08-15

...BRCA1, and XRCC4/5/6 correlates with poor survival in non-small cell lung cancer, whereas low ERCC1 expression and speci...

Yuan(Y),Zhang(L),Liao(J),Wang(B),Lu(L),Chu... Clin Transl Med 2026-08-00

...BRCA1 variants, raising the possibility that SMMN-FGT may be part of a broader BRCA1-associated phenotypic spectrum. Som...

Stracke(C),Kautz-Freimuth(S),Shukri(A),Iss... PLoS One None

Women with BRCA1/2 pathogenic variants (PVs) without a personal cancer history and with open family planning are in a ve...

Xu(Y),Lei(Q),Yang(S),Zhang(Y),Luo(X),Song(... Eur J Med Chem 2026-08-16

...BRCA1, BRCA2 and RAD51, thereby triggering enhanced DNA damage and cell apoptosis. Notably, in the BRCA wild-type MDA-MB...

Zhu(H),Fang(Y),Yang(M),Gao(T),Zhou(Y),Zhao... Transl Oncol 2026-08-17

...BRCA1 was selected for functional validation. Consistent with the bioinformatic analyses, BRCA1 was markedly upregulated...