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TP53 BRCA1 CRISPR single-cell cancer

Kim(Hye Sook),Lee(Soon Wook),Choi(Yoon Ji)... Cancer Res Treat 2015-07-13

...BRCA1 gene: 277_279delinsCC (Phe93fs). It is a novel BRCA1 mutation that has never been reported, and caused malignant l...

Ochs-Balcom(Heather M),Sun(Xiangqing),Chen... Cancer Epidemiol Biomarkers... 2015-11-10

...BRCA1 on chromosome 17 (-log10 P values in the range of 3.0-3.2) using both sibling-based and relative-based methods; th...

De Pascalis(Ivana),Pilato(Brunella),Mazzot... Oncol Rep 2015-08-11

...BRCA1 and BRCA2 mutation analysis. For these reasons, we stratified the 22 familial BC patients in two group: 'low-risk'...

Arai(Masami),Iwase(Takuji),Takazawa(Yutaka... Gan To Kagaku Ryoho 2015-01-20

...BRCA1. HBOC is a cancer susceptibility syndrome involving breast, ovarian, or prostate cancers due to germline mutation ...

Szasz(A Marcell),Szirtes(Ildiko),Tihanyi(B... Virchows Arch 2015-04-10

...BRCA1. A high Ki-67 index and p53 expression were noted. Sequencing of the most frequent 46 oncogenes with ionTorrent (A...

Churpek(Jane E),Walsh(Tom),Zheng(Yonglan),... Breast Cancer Res Treat 2015-09-28

...BRCA1 and BRCA2 genes and 20 % (13/65) carried mutations in PALB2, CHEK2, BARD1, ATM, PTEN, or TP53. The mutational alle...

Zghair(Abdulrazzaq N),Sharma(Rohit),Sharma... Curr Pharm Biotechnol 2015-08-31

...BRCA1 is the predominant marker gene responsible for estrogen regulation. However increased exposure to estrogen is not ...

Zhong(Qian),Shi(Ganggang),Zhang(Yanmei),Lu... Gene 2015-03-03

...BRCA1 in HCC 1937 cells, which is a BRCA1 deficient cell line, represses Pol III gene transcription. Expressing mutant o...

Okino(Yuki),Machida(Yuka),Frankland-Searby... J Biol Chem 2015-05-04

BRCA1-associated protein 1 (BAP1), which is frequently mutated in cancer, functions as a deubiquitinase (DUB) for histon...

Couch(Fergus J),Hart(Steven N),Sharma(Priy... J Clin Oncol 2015-04-20

...BRCA1 and BRCA2, in a large cohort of patients with triple-negative breast cancer (TNBC) unselected for family history o...

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