Germline inactivating variants in BRCA1 lead to a significantly increased risk of breast and ovarian cancers in carriers...
...BRCA1 and BRCA2. Inhibition of VEGFR3 in ovarian tumor cells was associated with growth arrest. CD133(+) ovarian cancer ...
...BRCA1 and BRCA2 genes. Obesity, hormone therapy and use of alcohol are possible causes and over-expression of leptin in ...
...BRCA1 gene related to inherited breast cancer, and the wild-type and mutant-type sequences were successfully discriminat...
...BRCA1, Chk2, and p53. Here we describe a series of assays that are often used to analyze cell cycle checkpoints after IR...
Majority of mutations found to date in the BRCA1/BRCA2 genes in breast and/or ovarian cancer families are point mutation...
...BRCA1 and BRCA2 has become incorporated in the diagnostic procedure of patients with breast and/or ovarian cancer. Since...
...BRCA1/2 mutation carriers and 57.1 % of BRCA1 mutation carriers. Conversely, two-thirds of TNBC patients carried BRCA1/2...
...BRCA1, BRCA2, and CHEK2, and then assessed by logistic regression.,Re-analysis of our ATM, BRCA1, and BRCA2 mutation scr...
...BRCA1-associated breast carcinomas on tissue microarrays. RNA-seq data from The Cancer Genome Atlas (TCGA) was used to c...
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