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TP53 BRCA1 CRISPR single-cell cancer

Abdel-Fatah(Tarek),Arora(Arvind),Agarwal(Dev… Breast Cancer Res Treat 2015-08-18

...BRCA1, low XRCC1, low SMUG1, low APE1 and low Polβ was also more likely in low DNA-PKcs expressing tumours (ps < 0.05). ...

Chen(Jianping),Li(Lin),Su(Jianyu),Li(Bing),C… PLoS One 2015-10-28

...Brca1 and phosphorylated p53. The results indicate the combinational application potential of NB and Cur in treatments o...

Tomimatsu(Nozomi),Mukherjee(Bipasha),Catheri… Nat Commun 2015-11-02

...BRCA1. In summary, phosphorylation of EXO1 by CDKs is a novel mechanism regulating repair pathway choice.

Yang(Yucai),Li(Chao),Yin(Li),Liu(Muyun),Wang… ACS Appl Mater Interfaces 2015-10-13

...BRCA1 in a 10 μL sample volume without any signal amplification process or the involvement of other synthesized complex,...

Zhao(Hongchang),Zhu(Min),Dou(Gelin),Zhao(Hon… Cell Cycle 2015-01-12

...BRCA1, RAD51, and the ubiquitinated DNA damage response factors. Taken together, our results demonstrate a novel functio...

Hanoch(Yaniv),Miron-Shatz(Talya),Rolison(Jon… Psychooncology 2015-08-03

...BRCA1/2 genetic test results. However, they encountered difficulties interpreting the uninformative and ambiguous BRCA1/...

Gupta(Arun),Hunt(Clayton R),Hegde(Muralidhar… Cell Rep 2015-08-24

...BRCA1 association. Decreased BRCA1 levels at DSB sites correlates with defective repairosome formation, reduced HR repai...

Yeo(Zhen Xuan),Wong(Joshua Chee Leong),Rozen… BMC Genomics 2015-02-20

...BRCA1 and BRCA2 genes. Our analysis revealed that false negative indels could be generated by TS under both default call...

Rosen(David B),Leung(Ling Y),Louie(Brent),Co… J Transl Med 2015-03-04

...BRCA1+/-) in HRR activity from BRCA1+/+ cell lines based on p-H2AX induction. Application of this assay to primary AML s...

Vazquez-Ortiz(Guelaguetza),Chisholm(Cristine… Breast Cancer Res 2015-04-16

...BRCA1/2), yet drug resistance frequently occurs during the treatment. Moreover, PARPis exhibit very little effect on can...

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