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[Promoter region methylation of DNA damage repair genes in human gastric cancer…

Guo(He),Yan(Wenji),Yang(Yunsheng),Guo(Mingzh… Zhonghua Yi Xue Za Zhi 2015-09-01

...BRCA1 and GSTpi in gastric cancer specimens. And MSP products were analyzed with 2% agarose gel electrophoresis.,The met...

Methylation profiling of ductal carcinoma in situ and its relationship to histo…

Pang(Jia-Min B),Deb(Siddhartha),Takano(Elena… Breast Cancer Res 2015-07-27

...BRCA1. RASSF1A was the most frequently methylated gene (90% of DCIS samples) and its methylation was associated with com...

Double-strand break repair-adox: Restoration of suppressed double-strand break …

Terasawa(Masahiro),Shinohara(Akira),Shinohar… Cancer Sci 2015-02-17

...BRCA1 localization to DSB sites, which is important to promote non-homologous end joining or homologous recombination, r...

BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a …

Burdak-Rothkamm(Susanne),Rothkamm(Kai),McCle… Cancer Lett 2015-03-03

...BRCA1 and FANCD2 foci formed in T98G bystander cells. Using ATR mutant F02-98 hTERT and ATM deficient GM05849 fibroblast...

BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferent…

Bai(Feng),Chan(Ho Lam),Scott(Alexandria),Smi… Cancer Res 2015-01-05

...BRCA1 expression in human breast cancers. Together, our findings showed that BRCA1 suppressed TWIST and EMT, inhibited L...

BRCA1 germline mutations may be associated with reduced ovarian reserve.

Wang(Erica T),Pisarska(Margareta D),Bresee(C… Fertil Steril 2015-01-29

...BRCA1 carriers, BRCA2 carriers, and women without BRCA mutations (controls). None had a personal history of breast or ov...

Role of the Na ⁺/K ⁺/2Cl⁻ cotransporter NKCC1 in cell cycle progression in huma…

Shiozaki(Atsushi),Nako(Yoshito),Ichikawa(Dai… World J Gastroenterol 2015-04-10

...BRCA1, and E2F5.,These results suggest that the expression of NKCC1 in ESCC may affect the G2/M checkpoint and may be re...

Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 pro…

Na(Zhenkun),Pan(Sijun),Uttamchandani(Mahesh)… Angew Chem Int Ed Engl 2015-05-13

...BRCA1 have been found in ca. 50% of hereditary breast cancers. Cell-permeable, small-molecule BRCA1 inhibitors are promi...

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1…

Kononenko(Artem V),Bansal(Ruchi),Lee(Nichola… Nucleic Acids Res 2015-01-27

...BRCA1. At the same time some functional aspects of BRCA1 are not fully understood. Here, a HAC (human artificial chromos...

Drug repurposing screen identifies lestaurtinib amplifies the ability of the po…

Vazquez-Ortiz(Guelaguetza),Chisholm(Cristine… Breast Cancer Res 2015-04-16

...BRCA1/2), yet drug resistance frequently occurs during the treatment. Moreover, PARPis exhibit very little effect on can...

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