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TP53 BRCA1 CRISPR single-cell cancer

Okino(Yuki),Machida(Yuka),Frankland-Searby(S… J Biol Chem 2015-05-04

BRCA1-associated protein 1 (BAP1), which is frequently mutated in cancer, functions as a deubiquitinase (DUB) for histon...

Couch(Fergus J),Hart(Steven N),Sharma(Priyan… J Clin Oncol 2015-04-20

...BRCA1 and BRCA2, in a large cohort of patients with triple-negative breast cancer (TNBC) unselected for family history o...

Jégu(M),Some Der(A),Morcel(K),Abadie(C),Frit… J Gynecol Obstet Biol Reprod … 2015-09-11

...BRCA1&2 are responsible in women for breast and ovarian cancers that commonly occur at a young age: as such, there are s...

Zheng(Li-Yuan),Song(Ai-Ping),Chen(Lan),Liu(D… Eur J Obstet Gynecol Reprod B… 2015-09-04

...BRCA1 and AURKA and clinicopathological parameters.,This study indicates that genetic polymorphisms of AURKA, BRCA1 and ...

Ganesan(Shanthi),Nteeba(Jackson),Keating(Ail… Toxicol Appl Pharmacol 2015-02-06

...Brca1), Rad 51 homolog (Rad51), poly [ADP-ribose] polymerase 1 (Parp1) and protein kinase, DNA-activated, catalytic poly...

Pickholtz(Itay),Saadyan(Shira),Keshet(Gilmor… Oncotarget 2015-10-20

...BRCA1-expressing cells. A complete knockdown of BRCA1 or p21waf1 renders the cells unresponsive to EB1089. Furthermore, ...

Ward(Ambber),Khanna(Kum Kum),Wiegmans(Adrian… Cancer Treat Rev 2015-02-19

...BRCA1 functional loss and PARP inhibition. In this review we suggest that clinical outcomes could be improved by additio...

Economopoulou(P),Dimitriadis(G),Psyrri(A) Cancer Treat Rev 2015-02-19

...BRCA1/2 mutations. During the past few years and thanks to technology evolution, we have been witnesses of an intensive ...

Molina-Montes(Esther),Pérez-Nevot(Beatriz),P… Breast 2015-08-24

BRCA1/2 mutation carriers are at a higher risk of breast cancer and of subsequent contralateral breast cancer (CBC). Thi...

Mancini-DiNardo(Debora),Judkins(Thaddeus),Wo… J Exp Clin Cancer Res 2015-09-22

...BRCA1 and BRCA2 (≈1,700) and Lynch syndrome/polyposis genes MLH1, MSH2, MSH6, APC, MUTYH, and EPCAM (≈2,200). We validat...

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