...BRCA1 gene are not the unique factor that could inactivate BRCA1 protein which leads to familial breast cancer onset wit...
...BRCA1/2 mutation carriers. Our aim was to determine whether validated susceptibility SNP scores improve the predictive a...
...Brca1) pathways in the mammary gland. Despite inactivation of all three tumor suppressors throughout the epithelium, low...
...BRCA1) were found either as deleted in one population or amplified in the other. Few chromosomal alterations were found ...
...BRCA1 mutations. In 7 Uighur patients with BRCA1 mutations, there were 11 unique sequence alterations in the BRCA1 gene,...
Mutational screening of the breast cancer susceptibility gene BRCA1 leads to the identification of numerous pathogenic v...
...BRCA1), beta-tubulin III (TUBB3), and microtubule-associated protein tau (MAPT).,Melittin had a synergistic effect on th...
...BRCA1/BARD1-dependent ubiquitination of γ-tubulin causes centrosome amplification. In the current study, we identified B...
...BRCA1 and ERCC1 (P < 0.0001) or RRM1 (P < 0.0001) mRNA levels. As BRCA1 levels increased, the probability of response in...
...BRCA1 associated protein-1 (BAP1) in 15% of tumors, including deleterious alterations to the deubiquitinase active site ...
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