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TP53 BRCA1 CRISPR single-cell cancer

Samama(Dikla),Hasson-Ohayon(Ilanit),Perry(Sh… Psychol Health Med 2015-10-26

...BRCA1/2 mutation women carriers. Forty asymptomatic carriers who attended BRCA1/2 clinics in Israel completed self-admin...

Alli(Elizabeth),Solow-Cordero(David),Casey(S… Cancer Res 2015-01-05

...BRCA1-associated malignancies. Mutant BRCA1 limits the base-excision DNA repair activity that addresses oxidative DNA da...

Liu(Joyce F),Barry(William T),Birrer(Michael… Lancet Oncol 2015-01-27

...BRCA1/2 mutations from nine participating US academic medical centres. We randomly allocated participants (1:1) accordin...

Bayraktar(Soley),Amendola(Laura),Gutierrez-B… Breast 2015-08-24

...BRCA1 and BRCA2 mutations, respectively. BRCA1-carriers had a higher likelihood of a positive family history (FH) of bre...

Zhao(Hui),Zhang(Huawei),Du(Yonghai),Gu(Xiaom… Tumour Biol 2015-03-10

...BRCA1 and ERCC1 (P < 0.0001) or RRM1 (P < 0.0001) mRNA levels. As BRCA1 levels increased, the probability of response in...

Zarrizi(Reihaneh),Menard(Julien Albert),Belt… Cancer Res 2015-07-08

...BRCA1/BARD1-dependent ubiquitination of γ-tubulin causes centrosome amplification. In the current study, we identified B...

Tan(Xiaohui),Peng(Jin),Fu(Yebo),An(Shejuan),… Breast Cancer Res 2015-07-27

...BRCA1 expression.,Our findings suggest that miR-638 plays an important role in TNBC progression via BRCA1 deregulation. ...

Wang(Erica T),Pisarska(Margareta D),Bresee(C… Fertil Steril 2015-01-29

...BRCA1 carriers, BRCA2 carriers, and women without BRCA mutations (controls). None had a personal history of breast or ov...

Hu(Yiduo),Petit(Sarah A),Ficarro(Scott B),To… Cancer Discov 2015-08-05

...BRCA1 and helps to maintain the stability of PARP1-BRCA1-RAP80 complexes. BRCA1 PARsylation is a key step in BRCA1 HRR c...

Ellberg(Carolina),Jernström(Helena),Broberg(… Genes Chromosomes Cancer 2015-05-21

...BRCA1/2 mutations on age at breast and ovarian cancer diagnosis. This study included 577 female BRCA1/2 mutation carrier...

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