Schüchner(Stefan),Tembe(Varsha),Rodriguez(... J Biol Chem 2005-04-19

...BARD1 gene is mutated in a subset of breast and ovarian cancers, implicating BARD1 as a potential tumor suppressor. BARD...

Choudhury(Atish D),Xu(Hong),Modi(Ami P),Zh... J Biol Chem 2005-08-16

...BARD1 protein, and many of its biological functions are mediated by the BRCA1-BARD1 complex. Here, we show that BARD1 is...

Baer(R) Breast Dis 2005-03-21

...BARD1) protein, a novel polypeptide that bears a striking structural resemblance to BRCA1, and hRAD51, a human homolog o...

Lane(Timothy F) Cancer Biol Ther 2005-05-19

...BARD1 complexes. Recent breakthroughs have centered on elucidating critical DNA repair and chromatin-remodeling function...

Henderson(Beric R) Bioessays 2005-11-15

The subcellular location and function of many proteins are regulated by nuclear-cytoplasmic shuttling. BRCA1 and BARD1 p...

Kleiman(Frida E),Wu-Baer(Foon),Fonseca(Dan... Genes Dev 2005-06-20

...BARD1 ubiquitin ligase activity. Significantly, siRNA-mediated knockdown of BRCA1 and BARD1 resulted in stabilization of...

Starita(Lea M),Horwitz(Andrew A),Keogh(Mic... J Biol Chem 2005-08-16

The breast- and ovarian-specific tumor suppressor BRCA1, when associated with BARD1, is an ubiquitin ligase. We have sho...

Rodriguez(José Antonio),Au(Wendy W Y),Hend... Exp Cell Res 2004-03-11

...BARD1. We propose that BRCT mutations alter nuclear targeting of BRCA1, and that this may contribute to the inhibition o...

ElShamy(Wael M),Livingston(David M) Nat Cell Biol 2004-11-09

...BARD1 in vivo or in vitro and exhibits unique nuclear immunostaining. Unlike BRCA1FL (or p220), BRCA1-IRIS also co-immun...

Choudhury(Atish D),Xu(Hong),Baer(Richard) J Biol Chem 2004-10-25

...BARD1 inhibits the formation of these conjugates, suggesting that BARD1 serves to stabilize BRCA1 expression in part by ...