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Large BRCA1 and BRCA2 genomic rearrangements in Polish high-risk breast and ova…

Rudnicka(Helena),Debniak(Tadeusz),Cybulski(C… Mol Biol Rep 2014-07-02

...BRCA1 mutations: 5382insC, C61G and 4153delA. To date, just a few single large genomic rearrangements (LGRs) of BRCA1 ge...

DNA double-strand break repair genotype and phenotype and breast cancer risk wi…

Wu(Hui-Chen),Delgado-Cruzata(Lissette),Mache… Cancer Causes Control 2014-06-19

...BRCA1 rs799917 also had higher EJ capacity (35.1 ± 9.2 %) than those with GG (26.4 ± 10.1 %, p = 0.02).,Overall, we foun...

BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids.

Chandramouly(Gurushankar),Kwok(Amy),Huang(Bi… Nat Commun 2014-04-01

...Brca1 mutant cells reveal a bias towards LTGC that is corrected by expression of wild-type but not cancer-predisposing B...

Risk of having BRCA1 mutation in high-risk women with triple-negative breast ca…

Tun(N M),Villani(G),Ong(K),Yoe(L),Bo(Z M) Clin Genet 2014-07-18

...BRCA1 mutation compared with non-TNBC phenotype, and approximately two in nine women with TNBC harbor BRCA1 mutation. Tr...

Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cell…

Wu(King-Chuen),Yang(Su-Tso),Hsu(Shu-Chun),Ch… Oncol Rep 2014-04-07

...BRCA1, MGMT and p53 was noted in the RAW264.7 cells. Results from the western blotting indicated that p53, MGMT, 14-3-3-...

Diffusion-weighted imaging of the high-risk breast: Apparent diffusion coeffici…

O'Flynn(Elizabeth A M),Wilson(Robin M),Allen… J Magn Reson Imaging 2014-11-18

...BRCA1/2 mutation carriers (mean age, 43 years) and 16 women postmantle irradiation (mean age 40 years) underwent diffusi...

Supplemental screening ultrasound increases cancer detection yield in BRCA1 and…

Bosse(Kristin),Graeser(Monika),Goßmann(Axel)… Arch Gynecol Obstet 2014-10-20

...BRCA1/2 mutation carriers.,Between 01/1997 and 10/2008 221 BRCA1/2 mutation carriers participated in a breast cancer scr...

Opposing roles for 53BP1 during homologous recombination.

Kakarougkas(Andreas),Ismail(Amani),Klement(K… Nucleic Acids Res 2014-01-22

...BRCA1 in this process. Previous studies have shown that 53BP1 is pro-non-homologous end-joining and anti-HR. Surprisingl...

Comparative genomic study of gastric epithelial cells co-cultured with Helicoba…

Wang(Fen),Luo(Li-Dan),Pan(Jian-Hua),Huang(Li… World J Gastroenterol 2014-01-09

...BRCA1, SMAD2, TRAF1, and HDAC6. Quantitative real-time polymerase chain reaction analyses verified that HDAC6 and TRFA1 ...

BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signalin…

Sung(M),Giannakakou(P) Oncogene 2014-05-15

...BRCA1, is a tumor-suppressor gene, whose expression has been correlated with taxane sensitivity in many solid tumors inc...

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