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PGD for hereditary breast and ovarian cancer: the route to universal tests for …

Drüsedau(Marion),Dreesen(Jos C),Derks-Smeets… Eur J Hum Genet 2014-08-04

...BRCA1 and BRCA2 mutation carriers based on haplotyping of, respectively, 6 (BRCA1) and 8 (BRCA2) microsatellite markers ...

Antiproliferative effects of pomegranate extract in MCF-7 breast cancer cells a…

Shirode(Amit B),Kovvuru(Prasad),Chittur(Srid… Mol Carcinog 2014-06-24

...BRCA1, BRCA2, and BRCC3. Downregulation of HR genes correlated with increased levels of their predicted microRNAs (miRNA...

The novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibi…

Dai(Yun),Chen(Shuang),Kmieciak(Maciej),Zhou(… Mol Cancer Ther 2014-02-24

...BRCA1), resulting in sharp increases in DNA damage, reflected by enhanced γ-H2A.X formation, and apoptosis. Moreover, le...

Primary squamous cell carcinoma of the endometrium unrelated to human papilloma…

Giordano(Giovanna),Pizzi(Silvia),Azzoni(Cinz… Pathol Oncol Res 2014-01-28

...BRCA1 and p16 promoters using specific PCRs. In this rare malignancy, we found allelic imbalance (AI) at 17p13.1 (P53). ...

NF-κB is a critical mediator of BRCA1-induced chemoresistance.

Harte(M T),Gorski(J J),Savage(K I),Purcell(J… Oncogene 2014-06-26

BRCA1 mediates resistance to apoptosis in response to DNA-damaging agents, causing BRCA1 wild-type tumours to be signifi...

Seventeen years after BRCA1: what is the BRCA mutation status of the breast can…

Oluwagbemiga(Lawal Abdulrazzaq),Oluwole(Atoy… Springerplus 2014-11-26

...BRCA1 and BRCA2 genes. PUBMED was searched using the following words in various combinations; 'Breast Cancer', 'BRCA1', ...

Validation, calibration and refitting of a familial breast cancer model in sist…

van Houwelingen(Hans C),Rebora(Paola),Reilly… Stat Med 2014-04-28

...BRCA1 and BRCA2 genes. The validity of the model for the Swedish data is checked by using a calibration model for breast...

Pervasive sequence patents cover the entire human genome.

Rosenfeld(Jeffrey A),Mason(Christopher E) Genome Med 2014-05-20

...BRCA1 has 15mers matching at least 689 other genes. Longer sequences (1,000 bp) still showed extensive cross-gene matche...

Synergistic anticancer activity of arsenic trioxide with erlotinib is based on …

Kryeziu(Kushtrim),Jungwirth(Ute),Hoda(Mir Al… Mol Cancer Ther 2014-02-24

...BRCA1. Finally, the combination treatment of ATO and erlotinib was also distinctly superior to both monotreatments again...

The complex genetic landscape of familial breast cancer.

Melchor(Lorenzo),Benítez(Javier) Hum Genet 2014-03-05

...BRCA1-, BRCA2-, and non-BRCA1/BRCA2-related cancers described up to date. Special emphasis deserves the coexistence of d...

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