...BRCA1/2 sequencing. The procedure was first tested on a training set of 62 control samples, and then blindly validated o...
...BRCA1 gene mutations: 5382insC, 185delAG and C61G.,Anonymous donors of the oocytes and control healthy blood samples wer...
...BRCA1, CHK2, and p53 leading to the induction of response genes such as CDKN1A (p21), GADD45A, and RRM2B that promote ce...
...BRCA1, FANCD2, RAD51, XPF, and PAR in relation to clinicopathological and survival data among 1240 paraffin-embedded bre...
...BRCA1, BRCA2, PTEN, ATM, TP53, CHEK2, PPM1D, CDH1, MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, PMS1, PMS2, BRIP1, RAD50, RAD51C...
...Brca1-deficient mammary epithelial cells, and treating with anti-progesterone delays mammary tumorigenesis in Brca1/p53 ...
...BRCA1, BRCA2, or PTEN gene defects with 20- to more than 200-fold greater potency than existing PARP1/2 inhibitors. BMN ...
BRCA1 or BRCA2 mutations predispose to cancer development, primarily through their loss of role in the repair of DNA dou...
...BRCA1 and BRCA2 genes explain less than 25% of the familial clustering of breast cancer, and additional susceptibility g...
...BRCA1/2 mutations or altered expression was not detectable in rhabdomyosarcoma cells; however, TDP1 knockdown and PARP-1...
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