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Ovarian cancer genome.

Imyanitov(Evgeny N) Methods Mol Biol 2014-03-17

...BRCA1, BRCA2, RAD51C, NBN (NBS1), BRIP, and PALB2. Sporadic ovarian cancers often phenocopy the features of BRCA1-relate...

Five-year analysis of magnetic resonance imaging as a screening tool in women a…

Kam(Jeffrey K P),Naidu(Paayal),Rose(Allison … J Med Imaging Radiat Oncol 2014-01-24

...BRCA1/BRCA2 mutation carriers, and one was found to be a carrier after the cancer was diagnosed. All four were identifie...

Cytochrome P450 2A13 is an efficient enzyme in metabolic activation of aflatoxi…

Zhang(Zhan),Yang(Xuejiao),Wang(Yun),Wang(Xic… Arch Toxicol 2014-04-07

...BRCA1, and γH2AX, were activated. All the above effects were inhibited by nicotine (a substrate of CYP2A13) or 8-MOP (an...

ZNF365 promotes stalled replication forks recovery to maintain genome stability.

Zhang(Yuqing),Park(Eunmi),Kim(Christopher S)… Cell Cycle 2014-03-20

...BRCA1 and BRCA2, which are important molecules required for DNA damage response. Previously, we demonstrated that ZNF365...

Increased proliferative background in healthy women with BRCA1/2 haploinsuffici…

Nisman(Benjamin),Kadouri(Luna),Allweis(Tanir… Cancer Epidemiol Biomarkers P… 2014-08-22

...BRCA1 and BRCA2 mutations (P = 0.74). The sEGFR concentration was significantly higher in women with BRCA1 than in contr...

Breast cancer in women at high risk: the role of rapid genetic testing for BRCA…

Francken(Anne Brecht),Schouten(Philip C),Ble… Breast 2014-05-14

...BRCA1 and -2 gene due to a strong family history or young age at diagnosis. These questions concern topics such as 1. Ti...

Polymorphisms in DNA repair and apoptosis-related genes and clinical outcomes o…

Lee(Shin Yup),Kang(Hyo-Gyoung),Yoo(Seung Soo… Lung Cancer 2014-06-09

...BRCA1 rs799917 was significantly associated with both chemotherapy response and OS. XRCC1 rs25487 exhibited a significan...

copy number variation analysis in familial BRCA1/2-negative Finnish breast and …

Kuusisto(Kirsi M),Akinrinade(Oyediran),Vihin… PLoS One 2014-05-14

...BRCA1/2-founder mutations and pre-screened for the most common breast cancer genes) and 36 healthy controls were analyse...

Multiple susceptibility loci for radiation-induced mammary tumorigenesis in F2[…

Herrera(Victoria L),Ponce(Lorenz R),Ruiz-Opa… PLoS One 2014-03-18

...BRCA1 and BRCA2, have been identified accounting for 20% of breast cancer genetic risk, identification of other suscepti...

Opposing roles for 53BP1 during homologous recombination.

Kakarougkas(Andreas),Ismail(Amani),Klement(K… Nucleic Acids Res 2014-01-22

...BRCA1 in this process. Previous studies have shown that 53BP1 is pro-non-homologous end-joining and anti-HR. Surprisingl...

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