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Comparison of whole genome amplification and nested-PCR methods for preimplanta…

Michalska(Danuta),Jaguszewska(Kinga),Liss(Jo… Hered Cancer Clin Pract 2014-05-20

...BRCA1 gene mutations: 5382insC, 185delAG and C61G.,Anonymous donors of the oocytes and control healthy blood samples wer...

The highly prevalent BRCA2 mutation c.2808_2811del (3036delACAA) is located in …

Infante(Mar),Durán(Mercedes),Acedo(Alberto),… Carcinogenesis 2014-01-22

...BRCA1-c.68_69delAG, BRCA2-c.5946delT and c.8537delAG, are concentrated in hairpin loops, suggesting that these structure...

Evaluation of the pharmacodynamics and pharmacokinetics of the PARP inhibitor o…

Bundred(Nigel),Gardovskis(Janis),Jaskiewicz(… Invest New Drugs 2014-02-11

...BRCA1/2 germline mutations and in patients with homologous recombination deficiency. In this dose-finding study, patient...

Frequency of 5382insC mutation of BRCA1 gene among breast cancer patients: an e…

Chakraborty(Abhijit),Mukhopadhyay(Ashis),Bha… Fam Cancer 2014-05-22

...BRCA1 5382insC mutation in BC development in Eastern India, which may justify an extended BRCA1 5382insC testing within ...

Body image issues after bilateral prophylactic mastectomy with breast reconstru…

Gopie(Jessica P),Mureau(Marc A M),Seynaeve(C… Fam Cancer 2014-05-22

...BRCA1/2 mutation carriers can be potentially burdensome for body image and the intimate relationship. Therefore, in the ...

Comparison of the screening practices of unaffected noncarriers under 40 and be…

Duprez(Christelle),Christophe(Véronique),Mil… J Genet Couns 2014-01-21

...BRCA1/2 family-responded to a questionnaire on breast or ovarian cancer screenings they had undergone since receiving th...

Therapeutic applications of PARP inhibitors: anticancer therapy and beyond.

Curtin(Nicola J),Szabo(Csaba) Mol Aspects Med 2014-04-29

...BRCA1 and 2 mutations associated with familial breast and ovarian cancer, but there may be many other causes of HRR defe...

First description of an acinic cell carcinoma of the breast in a BRCA1 mutation…

Ripamonti(Carla B),Colombo(Mara),Mondini(Pat… BMC Cancer 2014-01-10

...BRCA1 mutation carriers has been already reported. Our findings further broaden the spectrum of BRCA1-associated breast ...

Nonequivalent gene expression and copy number alterations in high-grade serous …

George(Joshy),Alsop(Kathryn),Etemadmoghadam(… Clin Cancer Res 2014-01-28

...BRCA1/BRCA2 somatic or germline mutations and in those with BRCA1 DNA promoter methylation.,We describe gene expression ...

The T-box transcription factors TBX2 and TBX3 in mammary gland development and …

Douglas(Nataki C),Papaioannou(Virginia E) J Mammary Gland Biol Neoplasia 2014-04-30

...BRCA1/2-associated breast cancers and TBX3 overexpression has been associated with advanced stage disease and estrogen-r...

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