...BRCA1/2 mutant tumours, the therapeutic efficacy of these inhibitors in Ataxia-telangiectasia mutated (ATM)-mutated pros...
...BRCA1 and BRCA2 carriers, those with exogenous androgens exposure, and those had a prior oophorectomy. There were 50 phy...
...BRCA1, BRCA2, PTEN, TP53, BCL-2, BAX, Caspase-3, PI3K, AKT, and BRAD1 genes. Morphological changes associated with apopt...
...BRCA1-associated protein 1 (BAP1) gene emerged as a key factor protecting K562 leukemic cells from NK cell-mediated kill...
...BRCA1/2 and ATM. HRD-positive tumours were more common among non-endometrioid histologies, high-grade disease, and poor-...
...BRCA1 gene within a concentration range of 100-1500 nM, with a detection limit of 270 nM. Both assays enabled quantitati...
...BRCA1 knockout models, and syngeneic mouse models. Techniques such as immunohistochemistry, multiplex immunofluorescence...
...BRCA1, ESR1, and BCL2 were located at the center of the PPI network, and BRCA1 was identified as the core regulatory tar...
...BRCA1/BRCA2-mutated cancers. Despite this, acquired resistance to PARPi has become a major challenge in the clinic. Henc...
...BRCA1/2 genetic testing identified a pathogenic variant in BRCA1. The patient had previously lost her fourth child due t...
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