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Circulating estrogens and estrogens within the breast among postmenopausal BRCA…

Loud(Jennifer T),Gierach(Gretchen L),Veenstr… Breast Cancer Res Treat 2014-09-19

...BRCA1/2 mutation carriers. We conducted a study of PE/EM in serum, nipple aspirate fluid (NAF), and ductal lavage supern...

Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA r…

Li(Molong),Vattulainen(Sanna),Aho(Joonas),Or… Am J Respir Cell Mol Biol 2014-08-11

...BRCA1) as a novel target for BMPR2 signaling and a novel modulator of pulmonary EC homeostasis. We show here that BMPR2 ...

Development of breast tumors in CHEK2, NBN/NBS1 and BLM mutation carriers does …

Suspitsin(Evgeny N),Yanus(Grigory A),Sokolen… Med Oncol 2014-08-14

...BRCA1, 1 CHEK2/BLM, 1 CHEK2/BRCA1 and 1 NBN/BLM). Losses of heterozygosity affecting the wild-type allele were detected ...

Comprehensive sequencing of PALB2 in patients with breast cancer suggests PALB2…

Fernandes(Priscilla H),Saam(Jennifer),Peters… Cancer 2014-07-10

...BRCA1 or BRCA2 based on their personal and family history, and a "lower-risk" group consisting of 524 samples from patie...

NFκB mediates cisplatin resistance through histone modifications in head and ne…

Almeida(Luciana O),Abrahao(Aline C),Rosselli… FEBS Open Bio 2014-02-03

...BRCA1 levels and by promoting histone deacetylation (chromatin compaction). Activation of this molecular signature resul...

DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal …

Shang(Z),Yu(L),Lin(Y-F),Matsunaga(S),Shen(C-… Oncogenesis 2014-02-04

...Brca1 pathway, which impacts microtubule dynamics, kinetochore attachment and chromosomal segregation in mitosis. Downst...

Bilateral breast cancers.

Narod(Steven A) Nat Rev Clin Oncol 2014-10-29

...BRCA1 and BRCA2 mutations, but for women without such mutations, the decision to remove the contralateral breast is cont...

Estimating risks for variants of unknown significance according to their predic…

Dowty(J G),Lee(E),McKean-Cowdin(R),Henderson… Breast Cancer Res Treat 2014-10-01

...BRCA1 and no mutations in BRCA2 have previously been identified through the population-based Los Angeles County Cancer S...

Long-term prognosis of early-onset breast cancer in a population-based cohort w…

Nilsson(Martin P),Hartman(Linda),Idvall(Ingr… Breast Cancer Res Treat 2014-10-01

...BRCA1 and BRCA2 genes. Mutation carriers (n = 20) were compared with noncarriers (n = 201) for overall survival (OS) and...

Aurora-A controls cancer cell radio- and chemoresistance via ATM/Chk2-mediated …

Sun(Huizhen),Wang(Yan),Wang(Ziliang),Meng(Ji… Biochim Biophys Acta 2014-05-09

...BRCA1/2, ATR/Chk1, p53, pp53 (Ser15), H2AX, γH2AX (Ser319), and RAD51. Aurora-A inhibited the focus formation of γH2AX i...

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