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TP53 BRCA1 CRISPR single-cell cancer

Whiley(Phillip J),Parsons(Michael T),Leary(J… PLoS One 2014-12-22

Rare exonic, non-truncating variants in known cancer susceptibility genes such as BRCA1 and BRCA2 are problematic for ge...

Lee(Kyuwan),Cui(Yi),Lee(Luke P),Irudayaraj(J… Nat Nanotechnol 2014-10-31

...BRCA1, can be monitored at single-copy resolution by measuring the hybridization dynamics of the nanoplasmonic dimers. O...

Wei(J),Costa(C),Shen(J),Yu(L),Sanchez(J J),Q… Br J Cancer 2014-07-14

...BRCA1 attained a median survival of 36.6 months, compared with 13.9 months for those with high BRCA1 and low MMSET (P=0....

Savage(Kienan I),Gorski(Julia J),Barros(Elia… Mol Cell 2014-07-23

...BRCA1 predispose carriers to a high risk of breast and ovarian cancers. BRCA1 functions to maintain genomic stability th...

Dillenburg(Caroline Siviero),Almeida(Luciana… J Biomed Opt 2014-12-04

...BRCA1 DNA damage repair protein, a known genome protective molecule that actively participates in DNA repair. Our result...

Rabban(Joseph T),Garg(Karuna),Crawford(Beth)… Am J Surg Pathol 2014-06-26

...BRCA1 and BRCA2 gene testing; no germline mutations were identified in any patient. An additional 11 specimens contained...

Christou(Charita M),Kyriacou(Kyriacos) Biology (Basel) 2014-05-16

...BRCA1, which are the most well-characterized regions of the protein. The function of BRCA1 in DNA repair, transcription ...

Agboola(Ayodeji O J),Banjo(Adekunbiola A F),… Malays J Pathol 2014-08-21

...BRCA1, MDM2 (all p<0.001), p21 (p=0.006) and E-cadherin (p=0.001) and positively associated with P-cadherin (p=0.001), t...

Narod(S A),Tung(N),Lubinski(J),Huzarski(T),R… Curr Oncol 2014-04-25

...BRCA1 or BRCA2 carriers (relative risk: 2.1; 95% confidence interval: 1.4 to 3.0; p < 0.0001).,In a woman with a BRCA1 o...

Ashton-Prolla(Patricia),Vargas(Fernando Regl… Genet Mol Biol 2014-04-25

...BRCA1, BRCA2 and TP53.

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