Wang(B),Li(A),Li(X),Ho(PW),Wu(D),Wang(X),Liu… EMBO Rep 2018-00-00

...APPL2 in RIP-Cre neurons diminishes beiging in sWAT without affecting BAT, leading to cold intolerance and obesity in mi...

Yeo(JC),Wall(AA),Luo(L),Condon(ND),Stow(JL) Traffic 2016-00-00

...APPL2 has a dominant role in nuclear translocation of NF-KB p65 and it serves to constrain the secretion of pro- and ant...

Xu(S),Liu(D),Kuang(Y),Li(R),Wang(J),Shi(M),Z… J Immunol 2023-00-15

...APPL2 by stabilizing APPL2 mRNA. Knockdown of HuR or APPL2 impaired the migration and invasion of RA FLSs. Given its clo...

Canciglieri(PH),Kuga(GK),Muñoz(VR),Gaspar(RC… Life Sci 2018-10-01

...APPL2) content. The APPL isoform 1 (APPL1) and TRB3 (Tribbles homolog 3) contents were not altered. Akt phosphorylation ...

Urbanska(A),Sadowski(L),Kalaidzidis(Y),Miacz… Traffic 2011-09-00

...APPL2. They exhibit only limited colocalization with EEA1, another Rab5 effector and a marker of the canonical early end...

Miaczynska(M),Christoforidis(S),Giner(A),She… Cell 2004-02-06

...APPL2, two Rab5 effectors, which reside on a subpopulation of endosomes. In response to extracellular stimuli such as EG...

Chial(HJ),Wu(R),Ustach(CV),McPhail(LC),Moble… Traffic 2008-02-00

...APPL2) are homologous effectors of the small guanosine triphosphatase RAB5 that interact with a diverse set of receptors...

Rashid(S),Pilecka(I),Torun(A),Olchowik(M),Bi… J Biol Chem 2009-07-03

...APPL2 are novel activators of beta-catenin/TCF-mediated transcription. APPL proteins are multifunctional adaptors and ef...

Olchowik(M),Miaczyńska(M) Postepy Biochem 2009-00-00

...APPL2. These proteins specifically bind to the active form of Rab5, thus regulating the processes of docking and fusion ...

None Traffic 2016-00-00

...APPL2 labels the phagosomal membrane. Image produced by N. Condon. See Yeo et al. Traffic 2016; 17(9):1014-1026. Read th...