Gao(C),Chen(X),Xu(A),Cheng(K),Shen(J) Mol Neurobiol 2018-07-00

...APPL2 showed the potentials to modulate cell growth, but whether APPL2 could affect adult neurogenesis and animal mood b...

Gao(C),Yan(T),Chen(X),Cheng(KKY),Xu(A),Shen(… Neurosci Bull 2020-09-00

...APPL2 transgenic (Tg) mice. In the in vitro study, we found that APPL2 overexpression resulted in NSCs switching from ne...

Tan(Y),Xin(X),Coffey(FJ),Wiest(DL),Dong(LQ),… J Cell Physiol 2016-05-00

...Appl2 mice. We found that ubiquitous Appl2 knockout (Appl2-/-) mice, much like Appl1-/- mice, are viable and grow normal...

Nechamen(CA),Thomas(RM),Dias(JA) Mol Cell Endocrinol 2007-01-02

...APPL2. Though APPL1 and APPL2 show some similarity in primary sequence, APPL1 associates with Akt2, whereas APPL2 does n...

Cheng(KK),Zhu(W),Chen(B),Wang(Y),Wu(D),Sween… Diabetes 2014-11-00

...APPL2 overexpression but enhanced by APPL2 knockdown. Likewise, conditional deletion of APPL2 in skeletal muscles enhanc...

Mao(L),Lin(W),Nie(T),Hui(X),Gao(X),Li(K),Din… Cell Biosci 2014-00-00

...Appl2 are largely unknown. In the present study, the role of Appl2 in sepsis shock was investigated by using Appl2 knock...

Gao(C),Du(Q),Li(W),Deng(R),Wang(Q),Xu(A),She… Mol Neurobiol 2018-12-00

...APPL2 in olfactory functions. APPL2 Tg mice displayed higher GR activity and less capacity of neurogenesis at olfactory ...

Pyrzynska(B),Banach-Orlowska(M),Teperek-Tkac… Mol Oncol 2013-02-00

...APPL2 is independent of its endosomal localization. Cumulatively, our data indicate that a high level of APPL2 protein m...

Wang(B),Lin(H),Li(X),Lu(W),Kim(JB),Xu(A),Che… Proc Natl Acad Sci U S A 2020-00-10

...APPL2 impaired GSIS, leading to glucose intolerance in mice. APPL2 deficiency largely abolished glucose-induced first- a...

Ghalaei(A),Kay(M),Zarrinfam(S),Hoseinpour(P)… Mol Biol Rep 2018-12-00

...APPL2 gene expression alteration in breast cancer specimens and investigate OCC-1 variants overexpression effect on APPL...