...MRE11 nuclease as a LAGE3-interacting partner, and LAGE3 deficiency leads to unscheduled stalled forks degradation in an...
...MRE11, and FANCC. Of 950 patients analyzed, 364 (38.3%) harbored variants in HRR genes, with 266 (28%) carrying pathogen...
...MRE11(The endogenous MRE11 gene from Pichia pastoris) overexpression (The Meiotic Recombination 11, DNA double-strand br...
...MRE11) to PARP1 at DNA-damage sites in a kinase-activity-dependent yet cytokine-independent manner. Furthermore, TBK1 ac...
...MRE11 being particularly affected. This study established a natural product-based targeting strategy, identifying baical...
...MRE11/MRE11-RAD50-NBS1 (MRN) perturbation. Single-cell analyses identify CRABP2 as a fibroblast-enriched gene upregulate...
...MRE11-deficient mouse spermatocytes, which do not resect their DSBs, deletions at double cuts occur readily, with end-jo...
...MRE11-RAD50-NBS1 (MRN) complex, rather than MUS81 or ERCC1/XPF, was the principal mediator of cruciform DNA processing f...
...MRE11, Ku80, RNF168, and 14-3-3σ. Genetic studies have further demonstrated its importance in embryogenesis and male fer...
...MRE11 and pATM in the chromatin regions surrounding a DSB. Furthermore, local changes in spatial H3K9me3 heterochromatin...
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