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SenExo-cCCT2 Reprograms Senescence Response and Anti-Tumor Immunity Following F…

Zhu(S),Chen(Y),Lin(H),Lu(J),Pan(Y),Li(G),Wu(… Adv Sci (Weinh) 2025-10-00

...SLX4 condensate-mediated DNA damage repair pathways by regulating small ubiquitin-like modifier conjugation, thereby pro...

A panel incorporating genetic variants of RIN3, NLRC3, and SLX4 shows promise i…

Chen(PK),Chen(YM),Cho(CF),Chen(JJJW),Wu(JC),… Clin Exp Rheumatol 2025-09-00

...SLX4 genes that were predictive of achieving remission after tofacitinib therapy, and its results were completely consis...

TopBP1 coordinates DNA repair synthesis in mitosis via recruitment of the nucle…

Bagge(J),Petersen(KV),Karakus(SN),Nielsen(TM… Commun Biol 2025-07-04

...SLX4. Additionally, we demonstrate that the recruitment of SLX4 to TopBP1 foci in mitosis depends on TopBP1-K704, SLX4-T...

SLX1 silencing overcomes Olaparib resistance in metastatic castration-resistant…

Zhao(X),Feng(S),Nitie(X),Muluo(S),Lei(Y) Cancer Biol Ther 2025-12-00

...SLX4 endonuclease complex, in Olaparib resistance. Data from The Cancer Genome Atlas (TCGA) were used for expression and...

Potential role of Fanconi anemia pathway in the pathogenesis of endometrial can…

Yao(M),Liu(C),Ping(H),Meng(K),Li(X),Li(Q),Qi… Mol Med Rep 2025-11-00

...SLX4, FANCQ/XPF, FANCR/RAD51, FANCS/BRCA1, FANCT/UBE2T, FANCU/XRCC2, FANCV/REV7, FANCW/RFWD3), endometrial cancer (type ...

RNF4 and USP7 coordinate spatial regulation of SLX4 stability within the PML nu…

Jung(E),Kim(MJ),Schärer(OD),Kim(Y) Nucleic Acids Res 2025-09-23

...SLX4 stability. In PML NBs, the stability of SLX4 is maintained by the deubiquitinase USP7, managing the amount of SLX4 ...

Genetic Variants Associated with Breast Cancer Are Detected by Whole-Exome Sequ…

Van Tung(N),Lien(NTK),Huan(LD),Phuong(PC),Ma… Diagnostics (Basel) 2025-08-28

...SLX4, SPTBN1, TP53, WRN, and XRCC3 in 41 patients. Among them, 12 variants were novel, and 10 variants were assessed as ...

Alterations of DNA repair genes in the NCI-60 cell lines and their predictive v…

Sousa(Fabricio G),Matuo(Renata),Tang(Sai-Wen… DNA Repair (Amst) 2016-01-21

...SLX4 (FANCP/BTBD12) stood out among the genes most significantly related with DNA synthesis and topoisomerase inhibitors...

A novel protein, Rsf1/Pxd1, is critical for the single-strand annealing pathway…

Wang(Hanqian),Zhang(Zhanlu),Zhang(Lan),Zhang… Mol Microbiol 2016-09-08

...Slx4 are not principal agents in the SSA repair pathway in fission yeast. This is in marked contrast to the function of ...

Physical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biologic…

Hashimoto(Keiji),Wada(Kunio),Matsumoto(Kyomu… DNA Repair (Amst) 2016-06-23

...SLX4-interacting region, we suspected the disruption of the interaction with SLX4 in these XPF mutants, thereby causing ...

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