...SPO11 and DMC1. On the 3rd week, the cells de-polyploidised and returned to the normal cycle, telomerase, and mitosis. A...
...Spo11-induced DSBs, and that break-induced replication and hyper-resection of DSBs are the primary mechanisms underlying...
Spo11-mediated DNA double-strand breaks (DSBs) are essential for meiotic recombination, yet how Spo11 activity is tempor...
...Spo11-oligonucleotide covalent intermediates to sequencing protein-bound single-stranded DNA (ssDNA), in situ DNA end la...
...Spo11-independent meiosis in synthetic single-chromosome Saccharomyces cerevisiae, the complete deletion of all 300 spli...
...SPO11, MEI1, REC114, ANKRD31, DMC1, CNTD1, MLH3, SYCE1, and SYCP2), while three male patients carried MEIKIN variants. F...
...SPO11-TOPOVIBL catalytic machinery together with accessory proteins on the chromosome axis, linking recombination initia...
...SPO11, and DMC1, play essential roles in crossover formation and genome stability, with mutations in these genes often l...
...Spo11-induced DSBs. Recruitment of Mre11 to meiotic DSB sites depends on Rec114-Mei4 and Mer2 (RMM) that organize the me...
...Spo11 or the mechanisms that drive meiotic pairing.
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