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Repair and misrepair of telomeric DNA in dynamic interactions with PML nuclear …

Salmina(K),Rumnieks(F),Pjanova(D),Vainshelba… Nucleus 2026-12-00

...SPO11 and DMC1. On the 3rd week, the cells de-polyploidised and returned to the normal cycle, telomerase, and mitosis. A...

Break-induced replication forms long mutable single-strand DNA during meiosis.

Twarowski(JM),Kramara(J),Seuferer(GJ),Rennin… Nat Commun 2026-06-20

...Spo11-induced DSBs, and that break-induced replication and hyper-resection of DSBs are the primary mechanisms underlying...

Adaptive Spo11 RNA editing gate optimizes meiosis I pace and mitotic proliferat…

Wu(M),Liu(J),Han(J),Huang(J),Feng(C),Jiang(C… Sci Adv 2026-06-12

Spo11-mediated DNA double-strand breaks (DSBs) are essential for meiotic recombination, yet how Spo11 activity is tempor...

Mapping Meiotic Recombination DNA Double-Strand Breaks (DSBs) Hotspots -Methodo…

Bao(J) Adv Genet (Hoboken) 2026-09-00

...Spo11-oligonucleotide covalent intermediates to sequencing protein-bound single-stranded DNA (ssDNA), in situ DNA end la...

A spliceosome-independent eukaryote generated by complete intron removal.

Man(X),Zhang(WT),Zhang(YD),Li(QX),Dai(P),Jia… Cell 2026-07-23

...Spo11-independent meiosis in synthetic single-chromosome Saccharomyces cerevisiae, the complete deletion of all 300 spli...

Meiotic gene variants contribute to recurrent blastulation failure.

Chen(X),Leng(L),He(W),Li(W),Li(L),Zhang(X),X… Hum Reprod Open None

...SPO11, MEI1, REC114, ANKRD31, DMC1, CNTD1, MLH3, SYCE1, and SYCP2), while three male patients carried MEIKIN variants. F...

Multiscale Regulation of Meiotic Recombination in Mammals.

Shaheen(N),Menendez(AM),Pratto(F) Biol Reprod 2026-09-22

...SPO11-TOPOVIBL catalytic machinery together with accessory proteins on the chromosome axis, linking recombination initia...

Exploring Meiotic Recombination and Its Potential Benefits in South African Bee…

Magagula(NA),Ncube(KT),Zwane(AA),Mtileni(B) Vet Sci 2025-07-16

...SPO11, and DMC1, play essential roles in crossover formation and genome stability, with mutations in these genes often l...

Recruitment of Mre11 to recombination sites during meiosis.

Priyadarshini(P),Survi(M),Yazidi Mouloud(WE)… bioRxiv 2025-07-08

...Spo11-induced DSBs. Recruitment of Mre11 to meiotic DSB sites depends on Rec114-Mei4 and Mer2 (RMM) that organize the me...

Meiotic Recombination May Be Initiated by Copy Choice During DNA Synthesis Rath…

Jia(L),Yin(N),Wang(X),Li(J),Li(L) Int J Mol Sci 2025-09-27

...Spo11 or the mechanisms that drive meiotic pairing.

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