Singh(DK),Mahlandt(A),Durand(S),Jolivet(S),W… Curr Biol 2026-04-20

...spo11 osd1 haploid plants. We show that monopolar orientation involves all four cohesin subunits (REC8, SCC3, SMC1, and ...

Priyadarshini(P),Survi(M),El Yazidi Mouloud(… Nat Commun 2026-04-07

...Spo11-mediated programmed DSB formation to initiate homologous recombination. Recruitment of Mre11 to meiotic DSB sites ...

Surarapu(LK),Tilton(K),Stritto(MRD),Acharya(… bioRxiv 2026-05-29

...SPO11-dependent DSBs at recombination hotspots during early prophase. DSBs are resected normally and accumulate strand-e...

Grilli(S),Vertsimakha(O),Marston(L),Gonzalez… Nat Commun 2026-04-11

...spo11 and vasa1, in the malaria vector Anopheles gambiae. These promoters display distinct temporal and spatial expressi...

Gu(H),Zhang(T),Yuan(Y),Teng(H) Biology (Basel) 2026-03-30

...SPO11 displayed considerable downregulation post Pcbol silencing, with molecular docking predicting a strong affinity be...

Tang(X),Tong(MH) Trends Biochem Sci 2026-04-00

...SPO11-TOP6BL, together with its accessory proteins, initiate meiotic recombination, a process central to meiosis. In mam...

Raices(M),Balmir(F),Silva(N),Li(W),Grundy(MK… Elife 2026-03-25

...Spo11 catalyzes DSBs, additional regulatory proteins-referred to as 'Spo11 accessory factors'-regulate the number, timin...

Bian(Z),Wilhoit(K),Liber(J),Peer(A),Xu(Z),Ma… Proc Natl Acad Sci U S A 2026-06-02

...SPO11, are critical for stable inheritance of a diploid genome in the daughter cells. Specifically, deletion of these ge...

Liloku(P),Melo(DA),Gisbert(VG),Mannaert(S),M… Nucleic Acids Res 2026-08-10

The formation of DNA double-strand breaks (DSBs) by Spo11 is tied to the loop-axis organization of meiotic chromosomes. ...

Lukaszewicz(A),Wilson(TE),Kim(S),Keeney(S),J… Genes Dev 2026-08-26

SPO11 forms hundreds of double-strand breaks (DSBs) to initiate meiotic recombination that is normally error-free. Howev...