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Thymus-like phenotype in benign lymphoepithelial neoplasms of salivary glands: …

Agaimy(A),Laco(J),Schubart(C),Stoehr(R),Töge… Virchows Arch 2026-05-00

...TAF1 + WISP3, DNMT3A, and BCOR. Targeted RNA sequencing revealed a YAP1::MAML2 fusion in 1/7 cases. This is the first sy...

SAGA subunits Spt3 and Spt8 act directly and non-redundantly with TFIID in TBP …

Singh(S),Hinnebusch(AG) Nucleic Acids Res 2025-07-08

...Taf1 generally reduced TBP recruitment at these and most other SAGA-dependent genes only in cells lacking Spt3 or Spt8. ...

Therapeutic targeting of alternative splicing caused by a lethal noncoding stru…

Yadav(R),Vaine(CA),Domingo(A),Reed(S),Shah(S… medRxiv 2025-10-13

...TAF1 is a mechanistic hallmark of XDP. We leveraged postmortem brain samples from an XDP-specific brain bank to demonstr...

Key genetic determinants of diabetes remission in patients with obesity followi…

Mahjoubin-Tehran(M),Talebloo(J),Gadde(KM),Su… Updates Surg 2025-12-00

...TAF1, and BCLAF1 were recognized as the most significant transcription factors, and CSNK2A1, CDK1, and MAPK14 were found...

Mechanistic insights into DNA binding by BD1 of the TAF1 tandem bromodomain mod…

Yadav(Y),Chyne(P),Sudhamalla(B) Biochem J 2025-09-30

...TAF1 BD1 as a critical determinant for DNA interaction, providing mechanistic insight into how TAF1 tandem bromodomains ...

Myelin pathology is a key feature of X-linked Dystonia Parkinsonism.

Prakash(P),Limberg(KC),Zhang(W),Zhao(Y),Labo… bioRxiv 2025-10-08

...Taf1/TAF1 gene (hyTAF1) containing the pathogenic SVA_F insertion. We activated the hyTAF1 in Nestin+ neural progenitor ...

Genome writing to dissect consequences of SVA retrotransposon disease X-Linked …

Zhang(W),Zhao(Y),Prakash(P),Appleby(HL),Barr… bioRxiv 2025-10-08

...TAF1 gene. Here, we genomically rewrote a portion of the mouse Taf1 allele with the corresponding 78-kb XDP patient deri...

The role of uncharacterized protein Taf1 in regulating ATP levels and virulence…

Ma(Y),Pan(K),Shen(L),Qu(J),Han(Y),Cao(C),Xue… BMC Microbiol 2025-08-05

...Taf1, encoded by the gene CNAG_04232. We found that the deletion of the TAF1 gene resulted in the upregulation of 204 ge...

Activation of CISD2 as a protective strategy against doxorubicin-induced cardio…

Chou(YJ),Yeh(CH),Chen(CF),Lo(CJ),Yang(JH),Ch… Redox Biol 2025-10-00

...TAF1 and TCF12. Fourthly, analysis of transcriptomic and metabolomic datasets reveals that hesperetin protects the heart...

Chemoselective Tagging of Protein Methacrylation.

Gao(M),Wan(Q),Zhou(S),Wu(P),Nie(W),Chen(S) J Am Chem Soc 2025-11-26

...TAF1, TACC1, and SETD3, providing new targets for the study of epigenetic regulation. This study provides an effective m...

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