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The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myelobla…

Murata(Y),Kudoh(T),Sugiyama(H),Toyoshima(K),… FEBS Lett 1997-06-02

...WT1 correlates with poor prognosis in acute leukemia. In addition suppression of WT1 expression by WT1 anti-sense oligon...

High expression of WT1 gene in acute myeloid leukemias with more predominant WT…

Gu(W),Hu(S),Chen(Z),Qiu(G),Cen(J),He(B),He(J… Leuk Res 2010-01-00

...WT1+17AA isoforms expression (the ratio of WT1+17AA/WT1 more than 0.50). Interestingly the ratio of WT1+17AA/WT1 was sta...

[Application of HLA-A*0201/WT1 pentamer combined with intracellular IFNgamma+ s…

Wei(L),Sun(XD),Zuo(HL),Liu(TQ),Guo(M),Liu(GX… Zhongguo Shi Yan Xue Ye Xue Z… 2010-04-00

...WT1+CD8+ CTL and WT1+IFNgamma+ cells did not detected in all 14 donors, but WT1+CD8+ CTL cells in 2 patients and WT1+IFN...

The Wilms' tumor gene WT1 can regulate genes involved in sex determination and …

Shimamura(R),Fraizer(GC),Trapman(J),Lau YfC,… Clin Cancer Res 1997-12-00

...WT1 isoforms without the KTS tripeptide, WT1(-)KTS, but was not activated by the WT1 isoforms with the KTS tripeptide, W...

Insights into the physiological role of WT1 from studies of genetically modifie…

Discenza(MT),Pelletier(J) Physiol Genomics 2004-02-13

...WT1 in genitourinary system development. Biochemical analysis of the different WT1 protein isoforms showed that WT1 is a...

Interaction of human genes WT1 and CML28 in leukemic cells.

Mao(X),Zhang(B),Liu(LL),Bai(XL),Zhang(DH) J Huazhong Univ Sci Technolog… 2013-02-00

...WT1 and CML28 in leukemic cell line K562 to examine the interaction between CML28 and WT1. WT1 and CML28 gene expression...

The Wilms' tumor suppressor Wt1 activates transcription of the erythropoietin r…

Kirschner(KM),Hagen(P),Hussels(CS),Ballmaier… FASEB J 2008-08-00

...Wt1 isoform, Wt1(-KTS), in regulating the expression of the erythropoietin receptor (EpoR). Wt1 and EpoR were coexpresse...

Internal translation initiation generates novel WT1 protein isoforms with disti…

Scharnhorst(V),Dekker(P),van der Eb(AJ),Joch… J Biol Chem 1999-08-13

...WT1, is homozygously mutated in a subset of Wilms' tumors. Heterozygous mutations in WT1 give rise to congenital anomali...

Wilms' tumor gene 1 regulates p63 and promotes cell proliferation in squamous c…

Li(X),Ottosson(S),Wang(S),Jernberg(E),Boldru… BMC Cancer 2015-05-01

...WT1 and p63 expression. Several known WT1 and p63 target genes were affected by WT1 knockdown. Protein interaction was d...

The Wilms tumor gene (WT1) (+/-KTS) isoforms regulate steroidogenesis by modula…

Meng(K),Wang(X),He(Y),Yang(J),Wang(H),Zhang(… Biol Reprod 2019-00-01

...WT1 encodes the splicing variants WT1(+KTS) and WT1(-KTS). Recent data suggest that WT1 plays an important role in the d...

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