Literature Search

Maertens(O),Johnson(B),Hollstein(P),Frederic… Cancer Discov 2013-03-00

...NF1 is mutated or suppressed in human melanomas that harbor concurrent BRAF mutations, NF1 ablation decreases the sensit...

Gitler(AD),Kong(Y),Choi(JK),Zhu(Y),Pear(WS),… Pediatr Res 2004-04-00

...NF1 are predisposed to juvenile myelomonocytic leukemia. The Nf1 gene encodes neurofibromin, which can function as a Ras...

Serra(E),Rosenbaum(T),Winner(U),Aledo(R),Ars… Hum Mol Genet 2000-12-12

...NF1(-/-) and NF1(+/-). These data strongly support the idea that NF1 mutations in SCs, but not in fibroblasts, correlate...

Thomas(SL),Deadwyler(GD),Tang(J),Stubbs(EB),… Biochem Biophys Res Commun 2006-09-29

...NF1) are deficient for the protein neurofibromin, which contains a GAP-related domain (NF1-GRD). Neurofibromin-deficient...

Heervä(E),Peltonen(S),Svedström(E),Aro(HT),V… Bone 2012-03-00

...NF1. Our aim was also to characterize the effects of bisphosphonates on NF1 osteoclasts in vitro. NF1 osteoclasts and os...

Ganapathy(S),Fagman(JB),Shen(L),Yu(T),Zhou(X… Oncotarget 2016-12-20

Nf1 mutations or deletions are suggested to underlie the tumor predisposition of NF1 (neurofibromatosis type 1) and few ...

Hutter(S),Piro(RM),Waszak(SM),Kehrer-Sawatzk… Hum Genet 2016-05-00

...NF1 patients at risk for tumor formation has been described, although enrichment for mutations in the 5' region of the N...

Douben(H),Hoogeveen-Westerveld(M),Nellist(M)… Hum Mutat 2023-00-00

...NF1) and Legius syndrome (LS) are caused by inactivating variants in NF1 and SPRED1. NF1 encodes neurofibromin (NF), a G...

López-Juárez(A),Titus(HE),Silbak(SH),Pressle… Cell Rep 2017-00-18

...Nf1+/- mouse brains, and cells containing active Notch are increased in NF1 patient WM. We thus identify Notch as an Nf1...

Chohan(H),Esfandiarei(M),Arman(D),Van Raamsd… PLoS One 2018-00-00

...NF1) is reduced. Despite this observation, gonadal function has not been examined in patients with NF1. In order to asse...