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TP53 BRCA1 CRISPR single-cell cancer

Larsen(Martin J),Thomassen(Mads),Tan(Qihua),… BMC Med Genomics 2014-09-03

...BRCA1/2-signatures, we identified 7 non-BRCA1/2 tumors with a BRCA1-like molecular phenotype and provide evidence for ep...

George(Sophia H L),Shaw(Patricia) Front Oncol 2014-06-24

...BRCA1 or BRCA2 genes have a substantial increased lifetime risk of developing epithelial ovarian cancer (EOC), and epide...

Lisowska(Katarzyna Marta),Olbryt(Magdalena),… Front Oncol 2014-01-30

...BRCA1 gene mutation; thus, it may be worthy of further testing. Our results confirm that histological tumor type may be ...

Guo(Mingzhou),Jia(Yan),Yu(Zhengtao),House(Mi… Discov Med 2014-10-16

...BRCA1 46%, p16INK4a 35%, p15INK4b 35%, RARβ 35%, and p73 33%. Overall, 94% of the tumors had methylation of at least one...

Krajc(M),Zadnik(V),Novaković(S),Stegel(V),Te… Clin Genet 2014-07-18

...BRCA1/2 genes, it is known that the wide spectrum of deleterious mutations shows high ethnic and geographic heterogeneit...

Anisimenko(Maksim S),Mitrofanov(Dmitriy V),C… Breast 2014-02-18

...BRCA1 gene (185delAG, T300G, 4153delA, and 5382insC) were estimated in the Russian population. The mutations were analyz...

Hallowell(Nina),Alsop(Kathryn),Gleeson(Marga… Genet Med 2014-01-10

...BRCA1 and BRCA2 genetic test information following participation in the Australian Ovarian Cancer Study.,Interviewees ha...

Giordano(Giovanna),Pizzi(Silvia),Azzoni(Cinz… Pathol Oncol Res 2014-01-28

...BRCA1 and p16 promoters using specific PCRs. In this rare malignancy, we found allelic imbalance (AI) at 17p13.1 (P53). ...

Harte(M T),Gorski(J J),Savage(K I),Purcell(J… Oncogene 2014-06-26

BRCA1 mediates resistance to apoptosis in response to DNA-damaging agents, causing BRCA1 wild-type tumours to be signifi...

Heemskerk-Gerritsen(B A M),Menke-Pluijmers(M… Ann Oncol 2014-04-22

...BRCA1 and BRCA2 mutation carriers.,Five hundred and seventy healthy female mutation carriers (405 BRCA1, 165 BRCA2) were...

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