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Therapeutic applications of PARP inhibitors: anticancer therapy and beyond.

Curtin(Nicola J),Szabo(Csaba) Mol Aspects Med 2014-04-29

...BRCA1 and 2 mutations associated with familial breast and ovarian cancer, but there may be many other causes of HRR defe...

Breast cancer size estimation with MRI in BRCA mutation carriers and other high…

Mann(R M),Bult(P),van Laarhoven(H W M),Span(… Eur J Radiol 2014-03-03

...BRCA1, 12 BRCA2 and 11 Non-BRCA patients). The size of the total tumor area (TTA) was compared to pathology. In invasive...

Interest of individuals from BRCA families to participate in research studies f…

Pal(Tuya),Vadaparampil(Susan),Kim(Jongphil),… Fam Cancer 2014-06-30

...BRCA1 and BRCA2 (BRCA) genes, the clinical significance of mutations in men remains incompletely defined. We sought eval...

Factors affecting the decision to undergo risk-reducing salpingo-oophorectomy a…

Kim(Dongwon),Kang(Eunyoung),Hwang(Euijun),Su… Fam Cancer 2014-06-30

...BRCA1 or BRCA2 mutations carriers in South Korea. The medical records of 124 women who had been found to have BRCA1 or B...

The expression of BRCA1, P53, KAI1, and Nm23 in ovaries of BRCA1 mutation carri…

Markowska(J),Bar(J),Mądry(R),Słomska(I),Mard… Arch Gynecol Obstet 2014-05-22

...BRCA1 mutation carriers as well as evaluate the expression of BRCA1, p53, Nm23, and KAI1 proteins in ovarian tissue from...

The complex genetic landscape of familial breast cancer.

Melchor(Lorenzo),Benítez(Javier) Hum Genet 2014-03-05

...BRCA1-, BRCA2-, and non-BRCA1/BRCA2-related cancers described up to date. Special emphasis deserves the coexistence of d...

Loss of BRCA1 expression leads to worse survival in patients with gastric carci…

Zhang(Zi-Zhen),Liu(Yuan Jie Charles),Yin(Xia… World J Gastroenterol 2014-04-25

...BRCA1 was significantly shorter than those with positive expression of BRCA1 (2-year survival rate, 32.4% vs 62.8%, P = ...

Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk amon…

Gilam(Avital),Edry(Liat),Mamluk-Morag(Efrat)… Breast Cancer Res Treat 2014-01-23

...BRCA1 gene using the Sequenom platform followed by Kaplan-Meier analysis. Additional data set of 378 Jewish BRCA1 carrie...

Synergistic anticancer activity of arsenic trioxide with erlotinib is based on …

Kryeziu(Kushtrim),Jungwirth(Ute),Hoda(Mir Al… Mol Cancer Ther 2014-02-24

...BRCA1. Finally, the combination treatment of ATO and erlotinib was also distinctly superior to both monotreatments again...

Outcome of BRCA1- compared with BRCA2-associated ovarian cancer: a nationwide s…

Vencken(P M L H),Reitsma(W),Kriege(M),Mourit… Ann Oncol 2014-04-22

...BRCA1 versus BRCA2 EOC patients.,Two hundred and forty-five BRCA1- and 99 BRCA2-associated EOC patients were identified ...

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