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USP39 reduces BRCA1 methylation to promote mitochondrial biogenesis and lower...

Wang(J),Li(X),Chang(J),Hou(X),Yan(Y),Chen(... 3 Biotech 2026-06-00

...BRCA1 expression by reducing methylation of the BRCA1 promoter. Furthermore, USP39 knockdown sensitized resistant cells ...

Health actions after direct-to-consumer genetic testing for medically actiona...

Sturm(AC),Detweiler(S),Bielenberg(J),Park(... Genet Med Open None

...BRCA1, BRCA2, APOB, LDLR, HFE, TTR, or MUTYH and had opened their report. Main outcomes included personal and family his...

Validation of LOH-Germline Inference Calculator of Variant Origin on Real-Wor...

Živić(K),Boljević(I),Matović(M),Nedeljkovi... JCO Precis Oncol 2026-05-00

...BRCA1/2 genes from tumor tissue is currently recommended as a companion diagnostic procedure for selection of patients e...

Bilateral risk reducing mastectomy uptake trends in healthy BRCA1/2 mutation ...

Bernini(M),Innocenti(S),Turchetti(D),Micco... World J Surg Oncol 2026-05-28

...BRCA1 and 89 BRCA2 carriers), 22.5% elected to undergo BRRM, with a significantly higher uptake among BRCA1 carriers (33...

Prognostic value of BAP1 expression in uveal melanoma: a comparative study wi...

Valencia Nieto(P),García Álvarez(C),García... Front Oncol None

...BRCA1-associated protein 1 (BAP1) nuclear expression in enucleated eyes with uveal melanoma (UM), and to compare its pre...

Finding novel vulnerabilities of hypomorphic BRCA1 alleles.

Schreuder(A),de Lint(K),Mỹ Phúc Võ(H),Góis... Mol Oncol 2026-05-29

...BRCA1 missense mutations and compare these to a BRCA1-depleted setting to study whether this affects screening for synth...

Platinum-based neoadjuvant chemotherapy and the predictive role of DNA damage...

Krasniqi(E),Di Benedetto(A),Filomeno(L),Ar... NPJ Breast Cancer 2026-05-29

...BRCA1/2 and other homologous recombination genes, and DDR activation was assessed centrally by phospho-DDR immunohistoch...

ENOX2 and the related mechanisms as potential genetic targets for varicose ve...

He(Q),Zhang(X),Tao(C),Chen(C),Yan(W) Medicine (Baltimore) 2026-05-29

...BRCA1, NCBP2, GTPBP4, HDAC2, KHDRBS1, and HNRNPR. Detailed functional enrichment analysis indicated involvement in tumor...

Environmental toxicant glyphosate induces cardiotoxicity: New insights from n...

Sun(M),Wang(Y),Tong(R),Yan(R),Pu(J) Medicine (Baltimore) 2026-05-29

...BRCA1, and PTGS2. Finally, we applied molecular docking analysis and revealed strong binding affinities, which suggested...

Microplastics as a Cross-Disease Driving Risk Factor in Lung Pathogenesis: An...

Ruan(H),Zhang(B),Xu(Q),Liu(Y),Zhang(D) J Appl Toxicol 2026-05-31

...BRCA1, and CCND1. Validation via database and single-cell analyses suggests that MP exposure may increase the risk of CO...

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