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Poly (ADP-ribose) polymerase 1 transcriptional regulation: a novel crosstalk be…

Li(Da),Bi(Fang-Fang),Cao(Ji-Min),Cao(Chen),L… Oncotarget 2014-12-04

...BRCA1-mutated ovarian cancer patients. Our findings imply that the genetic (such as BRCA1 mutation) and epigenetic mecha...

Should BRCA2 mutation carriers avoid neoadjuvant chemotherapy?

Raphael(J),Mazouni(C),Caron(O),Ferchiou(M),D… Med Oncol 2014-09-30

...BRCA1/2-negative (WT) patients with luminal B tumours, all treated with neoadjuvant anthracyclines±taxanes-based chemoth...

Randomized noninferiority trial of telephone versus in-person genetic counselin…

Schwartz(Marc D),Valdimarsdottir(Heiddis B),… J Clin Oncol 2014-04-21

Although guidelines recommend in-person counseling before BRCA1/BRCA2 gene testing, genetic counseling is increasingly o...

Surgically treated ovarian endometriosis association with BRCA1 and BRCA2 mutat…

Aviel-Ronen(Sarit),Soriano(David),Shmuel(Ely… Pathol Res Pract 2014-10-21

...BRCA1/2, most common among Ashkenazi Jews. The rate of mutations in each group was calculated and compared. BRCA1/2 muta...

HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-protea…

Wang(Xiaozhen),Lu(Guang),Li(Li),Yi(Juan),Yan… Biochem Biophys Res Commun 2014-04-22

...BRCA1-interacting protein involved in the control of BRCA1 protein level. HUWE1 binds BRCA1 through its N-terminus degro...

High prevalence of GPRC5A germline mutations in BRCA1-mutant breast cancer pati…

Sokolenko(Anna P),Bulanova(Daria R),Iyevleva… Int J Cancer 2014-05-14

...BRCA1, the major founder mutation in the Russian population, compared to wild-type BRCA1 BC cases [6/117 (5.1%) vs. 8/15...

Epstein Barr virus: a prime candidate of breast cancer aetiology in Sudanese pa…

Yahia(Zeinab A),Adam(Ameera Am),Elgizouli(Ma… Infect Agent Cancer 2014-03-17

...BRCA1 and BRCA2 in Sudanese breast cancer patients, the methylation status of six tumor suppressor genes was investigate...

[Hereditary ovarian carcinomas: clinico-biological features and treatment].

Floquet(Anne),Stoeckle(Eberhard),Croce(Sabri… Bull Cancer 2014-05-01

...BRCA1 and BRCA2 genes mutations, and the Lynch syndrome with mutated MMR genes is the other. Alterations in homologous r...

Decision-making on preimplantation genetic diagnosis and prenatal diagnosis: a …

Derks-Smeets(I A P),Gietel-Habets(J J G),Tib… Hum Reprod 2014-12-15

How do couples with a BRCA1/2 mutation decide on preimplantation genetic diagnosis (PGD) and prenatal diagnosis (PND) fo...

Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A…

Leung(Justin W),Agarwal(Poonam),Canny(Marell… PLoS Genet 2014-11-25

...BRCA1 recruitment to DNA damage. The acidic patch therefore is a critical nucleosome feature that may serve as a scaffol...

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