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Mitochondrial DNA variants and risk of familial breast cancer: an exploratory s…

Tommasi(Stefania),Favia(Paola),Weigl(Stefani… Int J Oncol 2014-11-13

...BRCA1/BRCA2 mutations, 14 sporadic BC patients and 20 healthy subjects were analyzed. In the D-loop and in the MTND4 reg...

Determinants of genetic counseling uptake and its impact on breast cancer outco…

Ayme(Aurélie),Viassolo(Valeria),Rapiti(Elisa… Breast Cancer Res Treat 2014-12-03

Genetic counseling and BRCA1/BRCA2 genes testing are routinely offered in a clinical setting. However, no data are avail...

Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 …

Metcalfe(Kelly),Gershman(Shelley),Ghadirian(… BMJ 2014-03-05

...BRCA1 and BRCA2 mutations and initially treated with unilateral or bilateral mastectomy. 181 patients had mastectomy of ...

Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results fr…

Phelan(C M),Iqbal(J),Lynch(H T),Lubinski(J),… Br J Cancer 2014-04-29

The BRCA1 and BRCA2 genes confer increased susceptibility to breast and ovarian cancer and to a spectrum of other cancer...

Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: c…

Yiannakopoulou(Eugenia) Cell Oncol (Dordr) 2014-09-29

...BRCA1 and BRCA2 mutations.,After excluding BRCA1 and BRCA2 mutations, factors proposed to contribute to familial breast ...

Cost-effectiveness of a genetic test for breast cancer risk.

Folse(Henry J),Green(Linda E),Kress(Andrea),… Cancer Prev Res (Phila) 2014-07-31

...BRCA1/2 mutations.

[Triple-negative breast cancer: molecular characteristics and potential therape…

Nowacka-Zawisza(Maria),Krajewska(Wanda Małgo… Postepy Hig Med Dosw (Online) 2014-05-29

...BRCA1 mutation carriers is also frequently TNBC. Triple-negative breast cancer does not benefit from hormonal therapies ...

Loss of BAP1 protein expression is an independent marker of poor prognosis in p…

Joseph(Richard W),Kapur(Payal),Serie(Daniel … Cancer 2014-07-10

...BRCA1 associated protein-1) occur in 5% to 15% of ccRCC cases and are associated with poor outcomes. The vast majority o...

The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer…

Xia(Qing),Cai(Yuchen),Peng(Roujun),Wu(Guoshe… Int J Oncol 2014-09-04

...BRCA1-mediated S phase checkpoint activation, but also for HR, because it phosphorylates BRCA1 for the efficient formati...

BRCA mutation carriers do not have compromised ovarian reserve.

Michaelson-Cohen(Rachel),Mor(Pnina),Srebnik(… Int J Gynecol Cancer 2014-10-14

Controversy exists about the impact of BRCA1/2 mutations on female fertility. Previous studies are small or based on ind...

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