...BRCA1 did not, confirming that the effect was BRCA1 specific. We demonstrated that Beclin 1 was activated in BRCA1 defic...
...BRCA1, low XRCC1, low FEN1, low SMUG1 and low pol β (ps < 0.0001). High MIB1 (p = 0.048), bcl-2 negativity (p < 0.0001) ...
...BRCA1 mutation. In six patients diagnosis was made during gestation, in the other six patients breast cancer was discove...
...BRCA1, at sites of DNA double-strand breaks (DSBs), whereas the localization of SUPT16H remained intact. Interestingly, ...
...Brca1 does not, suggesting that the role of Brca1 in HR is primarily to promote Rad51 filament formation, not to regulat...
...BRCA1-dependent process. K63-linked ubiquitin chains, which also form at IRIF, are also repositioned as well as receptor...
...BRCA1)/breast cancer 2, early onset (BRCA2), that have been markedly associated with the breast cancer phenotype exhibit...
...BRCA1 or BRCA2). Women with positive screening results should receive genetic counseling and, if indicated after counsel...
...BRCA1 and BRCA2) are associated with increased risks for breast, ovarian, and other types of cancer.,To review new evide...
...BRCA1 expression. Our results clearly demonstrate that hypermethylation of BRCA1 promoter is a frequent event in ovarian...
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