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Molecular testing in breast cancer.

Paoletti(Costanza),Hayes(Daniel F) Annu Rev Med 2014-09-30

...BRCA1 and -2 genes to determine high risk in unaffected women, selected tissue-based markers to determine prognosis and ...

A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Anti…

Inoue(Akira),Kikuchi(Sotaro),Hishiki(Asami),… J Biol Chem 2014-06-24

...BRCA1 in cisplatin-treated cells, suggesting that T2AA increases DSBs. When cells were treated by cisplatin and T2AA, th...

Surgically treated ovarian endometriosis association with BRCA1 and BRCA2 mutat…

Aviel-Ronen(Sarit),Soriano(David),Shmuel(Ely… Pathol Res Pract 2014-10-21

...BRCA1/2, most common among Ashkenazi Jews. The rate of mutations in each group was calculated and compared. BRCA1/2 muta...

HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-protea…

Wang(Xiaozhen),Lu(Guang),Li(Li),Yi(Juan),Yan… Biochem Biophys Res Commun 2014-04-22

...BRCA1-interacting protein involved in the control of BRCA1 protein level. HUWE1 binds BRCA1 through its N-terminus degro...

Distribution of BRCA1 and BRCA2 Mutations in Asian Patients with Breast Cancer.

Kim(Haeyoung),Choi(Doo Ho) J Breast Cancer 2014-06-24

...BRCA1 and BRCA2 (BRCA1/2) mutations in Asians are expected to be different than in Caucasians. The prevalence of BRCA1/2...

Inhibition of sepsis-induced inflammatory response by β1-adrenergic antagonists.

Ibrahim-Zada(Irada),Rhee(Peter),Gomez(Christ… J Trauma Acute Care Surg 2014-04-07

...BRCA1 motifs. Analysis of a human sepsis database identified the up-regulation of CAMP (p = 0.032) and TNFSF10 (p = 0.00...

Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutatio…

Kotsopoulos(Joanne),Lubinski(Jan),Moller(Pal… Breast Cancer Res Treat 2014-09-19

...BRCA1 mutation and the risk increases with duration of use. Caution should be taken when advising women with a BRCA1 mut...

Prognostic value of CtIP/RBBP8 expression in breast cancer.

Soria-Bretones(Isabel),Sáez(Carmen),Ruíz-Bor… Cancer Med 2014-09-04

...BRCA1 and retinoblastoma. Both its functions and interactors point to a putative oncogenic potential of CtIP/RBBP8 loss....

Dicycloplatin, a novel platinum analog in chemotherapy: synthesis of chinese pr…

Yu(Jing Jie),Yang(Xuqing),Song(Qinhua),Muell… Anticancer Res 2014-03-25

...BRCA1) and triple-phosphorylated p53, compared to controls. Cisplatin produced a similar profile, with increased p53 pro...

Platinum drugs and DNA repair mechanisms in lung cancer.

Bonanno(Laura),Favaretto(Adolfo),Rosell(Rafa… Anticancer Res 2014-03-25

...BRCA1); however, increasing biological knowledge about DNA repair pathways suggests the potential clinical usefulness of...

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