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TP53 BRCA1 CRISPR single-cell cancer

Zhang(Jian),Wang(Zhonghua),Hu(Xichun),Wang(B… Int J Cancer 2014-12-22

...BRCA1/2 mutation status and immunohistochemical basal markers were included in the correlative studies. Sixty-four patie...

Muñoz(Meilen C),Yanez(Diana A),Stark(Jeremy … Nucleic Acids Res 2014-09-02

...BRCA1. We have examined the domains of RNF168 important for these DDR events, including chromosomal HR that is induced b...

Yadav(Budhi Singh),Sharma(Suresh C),Chanana(… World J Clin Oncol 2014-06-24

...BRCA1 related breast cancers. This review evaluates the activity of available chemotherapy and targeted agents in TNBC. ...

Makowski(Liza),Zhou(Chunxiao),Zhong(Yan),Kua… Gynecol Oncol 2014-05-13

...Brca1 and p53, and inactivates the retinoblastoma (Rb) proteins in adult ovarian surface epithelial cells, via injection...

Mantia-Smaldone(Gina),Ronner(Lukas),Blair(An… Gynecol Oncol 2014-07-16

...BRCA1- ovarian cancers.,The immunophenotype of BRCA1- and wild-type (WT) ovarian cancer cells and their response to PLD ...

Walinda(Erik),Morimoto(Daichi),Sugase(Kenji)… J Biol Chem 2014-12-17

...BRCA1 gene 1) is a protein commonly found in ubiquitin-positive inclusions in neurodegenerative diseases. Due to its hig...

Osorio(Ana),Milne(Roger L),Kuchenbaecker(Kar… PLoS Genet 2014-11-24

...BRCA1 and BRCA2, given the relation of synthetic lethality that exists between one of the components of the BER pathway,...

Kast(Karin),Schmutzler(Rita K),Rhiem(Kerstin… Int J Cancer 2014-11-18

...BRCA1 or BRCA2 genes in families suspected of having hereditary breast and ovarian cancer. In 9,390 families, we determi...

Wei(J),Costa(C),Shen(J),Yu(L),Sanchez(J J),Q… Br J Cancer 2014-07-14

...BRCA1 attained a median survival of 36.6 months, compared with 13.9 months for those with high BRCA1 and low MMSET (P=0....

Tavtigian(Sean V),Chenevix-Trench(Georgia) Biomark Med 2014-12-17

...BRCA1, BRCA2, PALB2 and BRIP1 stand as examples where the majority of mutations lead to protein truncation;TP53 provides...

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